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pazinaclone

structure given in first source

Also Known As:

2-(7-chloro-1,8-naphthyridin-2-yl)-3-((1,4-dioxa-8-azaspiro(4.5)dec-8-yl)carbonylmethyl)isoindolin-1-one; DN 2327; DN-2327

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Isoindoles: 18
      - pazinaclone: 2
    - Naphthyridines: 2
      - pazinaclone: 2
Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Spiro Compounds: 2
      - pazinaclone: 2
Polycyclic Compounds: 6
- Spiro Compounds: 2
  - pazinaclone: 2

Related Diseases

1.	Body Weight (Weight, Body) 10/01/1996 - "During the substitution period, the decreases in body weight and food consumption in both S-(+)-DN-2327 and both diazepam groups were suppressed compared with those in the basal diet group. " 10/01/1996 - "After stopping the treatment, the body weight and food consumption in the diazepam 100 and 300 mg/kg groups tended to decrease or decreased to values lower than those in the control group, whereas these parameters in the S-(+)-DN-2327 30, 100 and 300 mg/kg groups were comparable to the control group values. "
2.	Ataxia (Dyssynergia) 01/01/1991 - "On the other hand, DN-2327 only slightly affected the motor coordination in mice and rats, as estimated by the inclined screen test and the climbing test, respectively; however, the compound attenuated the motor incoordination produced by diazepam. "

Related Drugs and Biologics

1.	Diazepam (Valium)