EM 16 (M-16)

structure given in first source

Also Known As:

M-16; 2-(2,6-dioxopiperidine-4-yl)phthalimidine; EM16

Networked: 12 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Carboxylic Acids: 973
  - Carbocyclic Acids
    - Phthalic Acids: 1
      - Phthalimides: 12
        Thalidomide: 4688
        EM 16: 12
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Piperidines: 17
    - Piperidones: 37
      - Thalidomide: 4688
        EM 16: 12
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Isoindoles: 18
      - Phthalimides: 12
        Thalidomide: 4688
        EM 16: 12

Experts

1.	Li, Zhaoxia: 1 article (02/2019)
2.	Liang, Jun: 1 article (02/2019)
3.	Wang, Daoai: 1 article (02/2019)
4.	Wu, Yang: 1 article (02/2019)
5.	Yang, Wenbin: 1 article (02/2019)
6.	Yu, Qiangliang: 1 article (02/2019)
7.	Zhou, Feng: 1 article (02/2019)
8.	Chen, Xiaoyan: 1 article (12/2016)
9.	Chen, Zhiye: 1 article (12/2016)
10.	Liu, Mengqi: 1 article (12/2016)

Related Diseases

1.	Echinococcosis (Hydatid Cysts) 02/01/1997 - "Antibody responses against Em18 and Em16 serodiagnostic markers in alveolar and cystic echinococcosis patients from northwest China." 07/01/1997 - "An immunoblot study to confirm the species-specificity of the diagnostic antigens Em18 and Em16 of Echinococcus multilocularis protoscolex extract showed that both antigens cross-reacted with sera from cystic echinococcosis (CE) patients. " 02/01/1997 - "Western blot analysis was carried out in order to evaluate new serodiagnostic markers, Em18 and Em16, for differentiation of alveolar echinococcosis (AE) from cystic echinococcosis (CE) using 36 serum samples from hydatid patients from Xinjiang, China, where AE and CE are both endemic and one double infection case has been reported. "
2.	Fibrosis (Cirrhosis) 11/01/2004 - "During the study period, 40 patients with a history of cirrhosis who required elective (E) or emergent (EM) surgical procedures under general anesthesia were reviewed (E = 24, EM = 16). "
3.	Alveolar echinococcosis 07/01/1997 - "The 18 kDa component was detectable by 75% of the sera from active alveolar echinococcosis (AE) patients, while only 31% detected Em16. " 07/01/1997 - "Immunoblot evaluation of the species-specificity of Em18 and Em16 antigens for serodiagnosis of human alveolar echinococcosis." 12/01/1995 - "Em18 and Em16, new serologic marker epitopes for alveolar echinococcosis in western blot analysis, are the only two epitopes recognized by commercially available weak positive (cut off) sera for Em2plus-ELISA." 02/01/1997 - "Western blot analysis was carried out in order to evaluate new serodiagnostic markers, Em18 and Em16, for differentiation of alveolar echinococcosis (AE) from cystic echinococcosis (CE) using 36 serum samples from hydatid patients from Xinjiang, China, where AE and CE are both endemic and one double infection case has been reported. "
4.	Carcinoma (Carcinomatosis) 03/01/2013 - "A média de anos decorridos desde o transplante foi oito anos (s = 4,61) e no exame objetivo diagnosticou-se cancro cutâneo não melanoma em 16% (20 / 127) dos doentes, com igual número de basaliomas e carcinomas espinocelulares. " 12/01/1995 - "M-16 also exhibited almost equivalent activities to MMC in vivo in terms of many biological profiles, i.e., antitumor activity against murine P388 leukemia, ascitic or solid B16 melanoma or human lung carcinoma xenograft L-27, and bone marrow toxicity in mice. "
5.	Secondary Headache Disorders 12/01/2016 - "Conventional MRI, 3D structure images, and rs-fMRI were performed in 18 patients with episodic migraines (EM), 16 patients with chronic migraine (CM), 44 patients with medication overuse headache plus chronic migraine (MOH + CM), and 32 normal controls (NC). "

Related Drugs and Biologics

1.	Antigens
2.	Protein Isoforms (Isoforms)
3.	PrPSc Proteins
4.	Complementary DNA (cDNA)
5.	Cadherins (E-Cadherin)
6.	Prions
7.	Peptide Hydrolases (Proteases)
8.	Epitopes

Related Therapies and Procedures

1.	Operative Surgical Procedures
2.	General Anesthesia
3.	Debridement