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4-isobutylamino-1,1-diphenyl-1-butanol maleate (AFD 19)

RN refers to maleate salt; structure in first source

Also Known As:

AFD 19; AFD-19

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Amino Alcohols: 20
    - 4-isobutylamino-1,1-diphenyl-1-butanol maleate: 1
- Alcohols: 595
  - Amino Alcohols: 20
    - 4-isobutylamino-1,1-diphenyl-1-butanol maleate: 1

Related Diseases

1.	Ventricular Tachycardia 07/01/1994 - "When administered 5 min before occlusion, 3 mg/kg of NS-2 and AFD-19 exhibited equivalent anti-arrhythmic activity to that of 5 mg/kg of disopyramide and mexiletine, as assessed by reductions in the number of premature ventricular complexes and in the incidences of ventricular tachycardia and ventricular fibrillation. "
2.	Ventricular Fibrillation 07/01/1994 - "When administered 5 min before occlusion, 3 mg/kg of NS-2 and AFD-19 exhibited equivalent anti-arrhythmic activity to that of 5 mg/kg of disopyramide and mexiletine, as assessed by reductions in the number of premature ventricular complexes and in the incidences of ventricular tachycardia and ventricular fibrillation. "

Related Drugs and Biologics

1.	Mexiletine (Mexitil)
2.	Disopyramide (Norpace)
3.	Anti-Arrhythmia Agents