Angiotensin II

An octapeptide that is a potent but labile vasoconstrictor. It is produced from angiotensin I after the removal of two amino acids at the C-terminal by ANGIOTENSIN CONVERTING ENZYME. The amino acid in position 5 varies in different species. To block VASOCONSTRICTION and HYPERTENSION effect of angiotensin II, patients are often treated with ACE INHIBITORS or with ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS.

Also Known As:

5-L-Isoleucine Angiotensin II; ANG-(1-8)Octapeptide; Angiotensin II, Isoleucine(5)-; Angiotensin II, Valine(5)-; Angiotensin-(1-8) Octapeptide; Isoleucine(5)-Angiotensin; Isoleucyl(5)-Angiotensin II; Valyl(5)-Angiotensin II; 5 L Isoleucine Angiotensin II; Angiotensin II, 5-L-Isoleucine; Angiotensin II, Ile(5)-; Angiotensin II, Val(5)-

Pharmalogical Action Categories:

Vasoconstrictor Agents

Hormones, Hormone Substitutes, and Hormone Antagonists
- Hormones: 80400
  - Peptide Hormones: 1347
    - Angiotensins: 6068
      - Angiotensin II: 14214
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Nerve Tissue Proteins: 2
    - Neuropeptides: 6772
      - Angiotensins: 6068
        Angiotensin II: 14214
- Peptides: 82426
  - Neuropeptides: 6772
    - Angiotensins: 6068
      - Angiotensin II: 14214
  - Peptide Hormones: 1347
    - Angiotensins: 6068
      - Angiotensin II: 14214
  - Oligopeptides: 519
    - Angiotensins: 6068
      - Angiotensin II: 14214
Biological Factors: 2472
- Inflammation Mediators: 1113
  - Autacoids: 276
    - Angiotensins: 6068
      - Angiotensin II: 14214

Sar(1)-Phe(4)-Ile(8)- angiotensin II

Bio-Agent Context: Research Results