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B fragment) dimer tissue plasminogen activator-(staphylococcal A

can rapidly reestablish cerebral perfusion after cerebral embolization

Also Known As:

tissue plasminogen activator-(staphylococcal A, B fragment) dimer; Fb-Fb-CF

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Blood Proteins: 12459
    - Blood Coagulation Factors: 5376
      - Plasminogen Activators: 5174
        Tissue Plasminogen Activator: 10595
        B fragment) dimer tissue plasminogen activator-(staphylococcal A: 3
  - Bacterial Proteins: 394
    - Staphylococcal Protein A: 2549
      - B fragment) dimer tissue plasminogen activator-(staphylococcal A: 3
    - Bacterial Antigens: 807
      - Staphylococcal Protein A: 2549
        B fragment) dimer tissue plasminogen activator-(staphylococcal A: 3
- Peptides: 82426
  - Peptide Fragments: 373
    - B fragment) dimer tissue plasminogen activator-(staphylococcal A: 3
Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Peptide Hydrolases: 23957
      - Serine Proteases: 3726
        Serine Endopeptidases: 11
        Tissue Plasminogen Activator: 10595
        B fragment) dimer tissue plasminogen activator-(staphylococcal A: 3
      - Endopeptidases: 633
        Serine Endopeptidases: 11
        Tissue Plasminogen Activator: 10595
        B fragment) dimer tissue plasminogen activator-(staphylococcal A: 3
Biological Factors: 2472
- Antigens: 143924
  - Bacterial Antigens: 807
    - Staphylococcal Protein A: 2549
      - B fragment) dimer tissue plasminogen activator-(staphylococcal A: 3
- Blood Coagulation Factors: 5376
  - Tissue Plasminogen Activator: 10595
    - B fragment) dimer tissue plasminogen activator-(staphylococcal A: 3

Related Diseases

1.	Hemorrhage 10/01/1992 - "Postoperative bruising, bleeding, and swelling, to a lesser extent, were associated with SK and Fb-Fb-CF. " 03/01/1989 - "A small macroscopic hemorrhage within an infarct was seen in 1 Fb-Fb-CF-treated animal in the 15-minute experiment and in none of the controls. "
2.	Embolic Stroke 03/01/1989 - "Because this analogue has a long serum half-life of 90 minutes, we employed Fb-Fb-CF in a rabbit cerebral embolic stroke model to assess its efficacy as a reperfusion agent. " 03/01/1989 - "The effects of a new tissue plasminogen activator analogue, Fb-Fb-CF, on cerebral reperfusion in a rabbit embolic stroke model." 04/01/1990 - "We evaluated two fibrinolytic agents, an analogue of tissue plasminogen activator (Fb-Fb-CF, the catalytic fragment of the tissue plasminogen activator molecule with a prolonged serum half-life, n = 10) and streptokinase (n = 7), in a rabbit model of embolic stroke. "
3.	Infarction (Infarctions) 03/01/1989 - "In the 90-minute experiment, macroscopic hemorrhagic infarction was seen in 4 Fb-Fb-CF-treated animals and in 3 controls.(ABSTRACT TRUNCATED AT 250 WORDS)" 03/01/1989 - "A small macroscopic hemorrhage within an infarct was seen in 1 Fb-Fb-CF-treated animal in the 15-minute experiment and in none of the controls. "

Related Drugs and Biologics

1.	Tissue Plasminogen Activator (Alteplase)
2.	Streptokinase
3.	Fibrinolytic Agents (Antithrombotic Agents)