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1-ethoxymethyl-5-fluorouracil

Also Known As:

EM-FU

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrimidines: 510
    - Pyrimidinones: 71
      - Uracil: 1493
        Fluorouracil: 26711
        1-ethoxymethyl-5-fluorouracil: 3

Related Diseases

1.	Yoshida Sarcoma 02/01/1989 - "After oral administration of BOF-A2 at 15 mg/kg to Yoshida sarcoma-bearing rats, BOF-A2 was hydrolyzed to EM-FU, CNDP and 5-FU, and their maximum concentrations in the blood were 2000 ng/ml, 300 ng/ml and 40 ng/ml, respectively. " 12/01/1993 - "Coadministration of CNDP with 1-ethoxymethyl-5-fluorouracil (EM-FU) to rats with Yoshida sarcoma elevated the level of 5-FU in both the blood and the tumor and enhanced the antitumor effect of EM-FU. "
2.	Neoplasms (Cancer) 05/01/1990 - "When BOF-A2 was given orally, blood levels of the main metabolites, EM-FU and CNDP, were maintained for a longer time in the tumor-bearing rats, and eventually the blood 5-FU levels were maintained over 12 hours. " 12/01/1993 - "Coadministration of CNDP with 1-ethoxymethyl-5-fluorouracil (EM-FU) to rats with Yoshida sarcoma elevated the level of 5-FU in both the blood and the tumor and enhanced the antitumor effect of EM-FU. "

Related Drugs and Biologics

1.	Fluorouracil (Carac)
2.	1-ethoxymethyl-5-fluorouracil
3.	Emitefur

Related Therapies and Procedures

1.	Oral Administration