AMF protocol

chemotherapy protocol consisting of the above cpds; used in treatment of gastric carcinoma & breast cancer

Also Known As:

AFM protocol; AFUM protocol; Duke AMF protocol; FAMTX protocol; FAMTX regimen; FAMeth protocol; MAF protocol

Networked: 10 relevant articles (0 outcomes, 1 trials/studies)

Therapy Context: Research Results

Therapeutics: 1158551
- Drug Therapy: 293145
  - Combination Drug Therapy: 12066
    - Antineoplastic Combined Chemotherapy Protocols: 35
      - AMF protocol: 10
  - Antineoplastic Protocols: 55
    - Antineoplastic Combined Chemotherapy Protocols: 35
      - AMF protocol: 10
- Clinical Protocols
  - Antineoplastic Protocols: 55
    - Antineoplastic Combined Chemotherapy Protocols: 35
      - AMF protocol: 10
Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Polycyclic Aromatic Hydrocarbons: 2020
        Naphthacenes
        Anthracyclines: 9423
        Daunorubicin: 2641
        Doxorubicin: 35390
        AMF protocol: 10
Polycyclic Compounds: 6
- Polycyclic Aromatic Hydrocarbons: 2020
  - Naphthacenes
    - Anthracyclines: 9423
      - Daunorubicin: 2641
        Doxorubicin: 35390
        AMF protocol: 10
Carbohydrates: 22023
- Glycosides: 2119
  - Aminoglycosides: 5131
    - Anthracyclines: 9423
      - Daunorubicin: 2641
        Doxorubicin: 35390
        AMF protocol: 10
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrimidines: 510
    - Pyrimidinones: 71
      - Uracil: 1493
        Fluorouracil: 26711
        AMF protocol: 10
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Pteridines: 147
      - Pterins: 160
        Aminopterin: 248
        Methotrexate: 24010
        AMF protocol: 10

Experts

1.	Muthuchamy, Mariappan: 1 article (01/2016)
2.	Reddy, Doodipala Samba: 1 article (01/2016)
3.	Wu, Xin: 1 article (01/2016)
4.	Balthasar, Joseph P: 1 article (08/2003)
5.	Lobo, Evelyn D: 1 article (08/2003)
6.	Soda, David M: 1 article (08/2003)
7.	Boot, H: 1 article (08/2000)
8.	Craanen, M: 1 article (08/2000)
9.	Gerritsen, W R: 1 article (08/2000)
10.	Swart, M: 1 article (08/2000)

Related Diseases

1.	Stomach Neoplasms (Stomach Cancer) 05/01/1991 - "The FAMTX protocol should be the reference treatment in future clinical trials that seek to improve the therapeutic outcome in advanced gastric cancer." 06/01/1996 - "Chemotherapy with the FAMTX regimen is tolerable in patients with locally advanced gastric cancer, without an increase in operative morbidity or mortality. " 06/01/1990 - "Fifty patients with advanced gastric cancer underwent chemotherapy in accordance with the FAMTX protocol. " 09/01/1995 - "Twenty-two patients with locally advanced inoperable gastric cancer received neoadjuvant chemotherapy with a modified 5-fluorouracil, doxorubicin, methotrexate (FAMTX) regimen. " 08/01/2000 - "For advanced irresectible gastric cancer, sequential high-dose methotrexate and 5-fluorouracil (both on day 1) combined with adriamycin on day 15 (FAMTX regimen), cycled every 28 days, is a fairly effective but toxic treatment, with a high incidence of neutropenic fever, dose reductions and dose delays. "
2.	Carcinoma (Carcinomatosis) 02/01/1989 - "Forty-two patients with advanced gastric carcinoma underwent chemotherapy in accordance with the FAMTX protocol. " 10/01/1990 - "Fifty patients with locally far advanced or metastasizing gastric carcinoma were treated with 5-fluorouracil, adriamycin and methotrexate using a slightly modified FAMTX protocol. "
3.	Vomiting 01/01/1997 - "The FAMTX regimen caused more hematologic toxicity and serious infections, but ECF caused more emesis and alopecia. "
4.	Infections 01/01/1997 - "The FAMTX regimen caused more hematologic toxicity and serious infections, but ECF caused more emesis and alopecia. "
5.	Fever (Fevers) 08/01/2000 - "For advanced irresectible gastric cancer, sequential high-dose methotrexate and 5-fluorouracil (both on day 1) combined with adriamycin on day 15 (FAMTX regimen), cycled every 28 days, is a fairly effective but toxic treatment, with a high incidence of neutropenic fever, dose reductions and dose delays. "

Related Drugs and Biologics

1.	Methotrexate (Mexate)
2.	Fluorouracil (Carac)
3.	Doxorubicin (Adriamycin)

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)
2.	Neoadjuvant Therapy
3.	Drug Tapering