squamocin

02/10/2023 - "In this study, we report that Sq-2, a biotinylated squamocin monomer, has a favorable antitumour effect on MDA-MB-231 and SKBR3 breast cancer cells <italic>in vitro</italic>. "
02/10/2023 - "Sq-2, a novel biotin-squamocin compound, shows a significant inhibitory effect on the propagation of SKBR3 and MDA-MB-231 breast cancer cells. "

01/18/2006 - "We showed that squamocin was cytotoxic to all the cancer lines tested. "
01/01/2020 - "Most of them show comparable in vitro cytotoxicity against HeLa, A549 and HepG2 cancer cell lines as their parent compounds squamocin and bullatacin. "
02/08/2011 - "Squamocin modulates histone H3 phosphorylation levels and induces G1 phase arrest and apoptosis in cancer cells."
01/18/2006 - "We purified squamocin, a cytotoxic bis-tetrahydrofuran acetogenin, from the seeds of Annona reticulata and analyzed its biologic effects on cancer cells. "
02/01/2002 - "Squamocin is one of the annonaceous acetogenins and has been reported to have antiproliferative effect on cancer cells. "

07/01/2001 - "[Mechanism of apoptosis induced by squamocin in leukemia cells]."
02/01/2002 - "Involvement of caspase-3 activation in squamocin-induced apoptosis in leukemia cell line HL-60."

04/11/2006 - "Induction of G2/M phase arrest by squamocin in chronic myeloid leukemia (K562) cells."

05/01/2016 - "10 kinds of annonaceous acetogenins were selected for antitumor activity testing against human lung cancer cell line A549/Taxol and the structure activity relationship was analyzed.MTT assay was used to detect the inhibitory activities of 10 kinds of annonaceous acetogenins and positive drugs against A549/Taxol cells, respectively uvariamicin-Ⅲ(1), uvariamicin-Ⅱ(2), annosquacin D(3), desacetyluvaricin(4), annosquatin A(5), squamostatin D(6), bullatacin(7), squamocin(8), motrilin(9), annosquatin B(10), verapamil and cisplatin. "