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monochlorobimane

marker for glutathione

Networked: 10 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Pyrazoles: 61
      - monochlorobimane: 10

Experts

1.	Bragin, Denis E: 1 article (04/2010)
2.	Connor, John A: 1 article (04/2010)
3.	Müller, Wolfgang S: 1 article (04/2010)
4.	Ramamoorthy, Prabhu: 1 article (04/2010)
5.	Shi, Honglian: 1 article (04/2010)
6.	Zhou, Bo: 1 article (04/2010)
7.	Abe, Tsutomu: 1 article (02/2004)
8.	Kuruhara, Yoshitada: 1 article (02/2004)
9.	Miyake-Takagi, Keiko: 1 article (02/2004)
10.	Oshikawa, Sayuri: 1 article (02/2004)

Related Diseases

1.	Glutathione synthetase deficiency 05/01/1994 - "In this study, 5-oxoprolinuria fibroblasts (GM3877 cells) contained less GSH than normal diploid fibroblasts as determined by biochemical analysis and by flow cytometry using monochlorobimane. "
2.	Neoplasms (Cancer) 12/01/1986 - "The bivariate analysis (forward angle light scatter versus monochlorobimane fluorescence) of cells derived from these tumors gave excellent resolution of normal and tumor cells and demonstrated extensive heterogeneity in the tumor cell population with respect to GSH content per cell." 04/01/1991 - "Intracellular glutathione (GSH) levels for seven mammalian cell lines (four human tumors, two rodent, one monkey) were determined by flow cytometry following staining with monochlorobimane (MBCl), and the results were compared with GSH levels measured by the Tietze assay. " 08/15/1991 - "To determine the extent of thiol variation among tumor cell subpopulations, tumor cell suspensions were stained with the thiol-specific stain, monochlorobimane (MCB). "
3.	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 04/01/2010 - "Using two-photon imaging techniques with monochlorobimane as a glutathione (GSH) probe, we investigated GSH levels in both core and penumbra regions of an ischemic brain after middle cerebral artery occlusion. "
4.	HIV Infections (HIV Infection) 04/01/1996 - "In addition, increases in plasma Trx levels correlate with decreases in monochlorobimane staining (indicative of lower intracellular glutathione levels in PBMC) and with changes in surface antigen expression (CD62L, CD38 and CD20) that occur in the later stages of HIV infection. "
5.	Leukemia L1210 05/28/1993 - "Intracellular glutathione (GSH) content was measured by flow cytometry using monochlorobimane (mBCl) and by the enzymatic assay in a set of 6 sublines of murine L1210 leukemia cells made resistant to DNA-interacting agents having distinct mechanisms of action: L-phenylalanine mustard (L-PAM), 1,3-bis(2-chloroethyl)-I-nitrosourea (BCNU), cisplatin (DDP), N-deformyl-N-(4-N,N-bis(2-chloroethylamino) benzoyl) distamycin A (FCE 24517), doxorubicin (DX) and 3'-deamino-3' (2-methoxy-4-morpholinyl)-doxorubicin (FCE 23762). "

Related Drugs and Biologics

1.	Glutathione (Reduced Glutathione)
2.	Doxorubicin (Adriamycin)
3.	Suspensions
4.	Sulfhydryl Compounds (Thiols)
5.	Phenylalanine (L-Phenylalanine)
6.	Melphalan (Alkeran)
7.	Coloring Agents (Dyes)
8.	DNA (Deoxyribonucleic Acid)
9.	Cisplatin (Platino)
10.	Carmustine (FIVB)