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6- (5- methylimidazol- 1- yl)methyl- 2- naphthoic acid hydrochloride

RN given refers to HCl; RN for parent cpd not available 6/89

Also Known As:

HOE 944; HOE-944

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Imidazoles: 150
      - 6-(5-methylimidazol-1-yl)methyl-2-naphthoic acid hydrochloride: 1
Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Polycyclic Aromatic Hydrocarbons: 2020
        Naphthalenes: 18
        6-(5-methylimidazol-1-yl)methyl-2-naphthoic acid hydrochloride: 1
Polycyclic Compounds: 6
- Polycyclic Aromatic Hydrocarbons: 2020
  - Naphthalenes: 18
    - 6-(5-methylimidazol-1-yl)methyl-2-naphthoic acid hydrochloride: 1

Related Diseases

1.

01/01/1988 - "Experiments were carried out to lower the mortality (LD70-90) of rats in ovalbumin-induced anaphylactic (DA) shock and in endotoxin-induced (ET) shock, and of mice after injection of Platelet-activating Factor (PAF shock) comparing the effects of the cyclooxygenase (COX)-inhibitors aspirin (ASA), indomethacin, of the COX-/lipoxygenase (LOX)-inhibitors nordihydroguajaretic acid (NDGA), phenidone and X 86 (analogue of BW 755c), of the inhibitor of thromboxane (TX) synthesis HOE 944, of the TX-antagonist BM 13177, of the PAF-antagonist BN 52021 and of ketotifen. "

Related Drugs and Biologics

1.	4,5- Dihydro- 1- (3- (trifluoromethyl)phenyl)- 1H- pyrazol- 3- amine
2.	Thromboxanes
3.	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)
4.	Platelet Activating Factor
5.	Ovalbumin
6.	Lipoxygenase (Lipoxygenase-1)
7.	Ketotifen (Ketotifene)
8.	Indomethacin (Indometacin)
9.	Endotoxins
10.	Aspirin (Acetylsalicylic Acid)