cerebellar soluble lectin

endogenous 1200 kDa intracellular lectin with subunits of 31.5 and 33 kDa; it is found in brain and nerve tissues and in tight junctions; displays specificity for mannosyl-glycoprotein

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Networked: 6 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Related Diseases

1.	Multiple Sclerosis 01/01/1991 - "[Is Cerebellar Soluble Lectin a major immunological target in multiple sclerosis?]." 08/18/1990 - "Antibodies to cerebellar soluble lectin in multiple sclerosis." 06/23/1990 - "Antibodies to cerebellar soluble lectin CSL in multiple sclerosis." 01/01/1991 - "et al., Lancet, 1990, 335, 1482-1484) the authors showed that antibodies against the mannose-binding protein Cerebellar Soluble Lectin (CSL) are present in the cerebrospinal fluid of most multiple sclerosis patients. " 02/01/1992 - "Cerebrospinal fluid samples from 14 human immunodeficiency type 1 (HIV-1) seropositive patients in various stages of HIV infection were tested for the presence of autoantibodies to an endogenous manose-binding protein, the cerebellar soluble lectin (CSL), which has recently been found to be detected in a high proportion of patients with multiple sclerosis. "
2.	HIV Infections (HIV Infection) 02/01/1992 - "Cerebrospinal fluid samples from 14 human immunodeficiency type 1 (HIV-1) seropositive patients in various stages of HIV infection were tested for the presence of autoantibodies to an endogenous manose-binding protein, the cerebellar soluble lectin (CSL), which has recently been found to be detected in a high proportion of patients with multiple sclerosis. "
3.	Nervous System Diseases (Neurological Disorders) 06/23/1990 - "Cerebrospinal fluid samples from 239 patients with various neurological disorders were tested for the presence of autoantibodies to an endogenous mannose-binding protein, the cerebellar soluble lectin CSL, by means of an immunoblotting test with rat CSL as antigen. "
4.	Neoplasms (Cancer) 10/01/1993 - "The glycoprotein composition of various transformed cells or malignant tumors was analyzed and compared to their respective non-malignant control cells or tissues of several species, including man, using an endogenous carbohydrate-binding protein, the cerebellar soluble lectin CSL (Zanetta et al., J. "
5.	Infections 02/01/1992 - "Cerebrospinal fluid anti-cerebellar soluble lectin antibodies in human immunodeficiency virus type 1 infection."

Related Drugs and Biologics

1.	Antibodies
2.	Mannose-Binding Lectin (Mannan-Binding Lectin)
3.	Glycoproteins (Glycoprotein)
4.	Autoantibodies
5.	Lectins
6.	Ligands
7.	Carrier Proteins (Binding Protein)
8.	Antigens
9.	saccharide-binding proteins