nomilin

01/01/2020 - "Nomilin targets the Keap1-Nrf2 signalling and ameliorates the development of osteoarthritis."

03/01/2012 - "Administration of nomilin inhibited tumor nodule formation in the lungs (68%) and markedly increased the survival rate of the metastatic tumor-bearing animals. "
10/15/2011 - "Nomilin significantly inhibited tumor directed capillary formation. "
08/01/1989 - "The results for group III showed that nomilin was considerably less effective as an inhibitor of DMBA-induced neoplasia."
01/01/1989 - "The number of mice with tumors was reduced from 100 to 72%, and the number of tumors per mouse was significantly decreased as a result of nomilin treatment. "
03/01/2012 - "Nomilin showed an inhibition of tumor cell invasion and activation of matrix metalloproteinases. "

02/15/2021 - "In this study, limonin, nomilin and limonexic acid (LNA) were investigated for understanding the possible mode of cytotoxicity in cultured pancreatic cancer (Panc-28) cells. "

01/01/2013 - "Nomilin as an anti-obesity and anti-hyperglycemic agent."
07/08/2011 - "Our results suggest a novel biological function of nomilin as an agent having anti-obesity and anti-hyperglycemic effects that are likely to be mediated through the activation of TGR5."
01/01/2017 - "We previously showed that nomilin, a citrus limonoid, activates TGR5 and confers anti-obesity and anti-hyperglycemic effects in mice. "
07/08/2011 - "Anti-obesity and anti-hyperglycemic effects of the dietary citrus limonoid nomilin in mice fed a high-fat diet."

01/01/2020 - "Here, we describe nomilin (NOM), a triterpenoid with inflammation modulatory properties in variety of disorders. "
07/04/2023 - "Nomilin and its analogue obacunone alleviate NASH and hepatic fibrosis in mice via enhancing antioxidant and anti-inflammation capacity."