lifibrol

01/01/1991 - "The study compound was tolerated well, and safety laboratory parameters did not show any relevant alterations, K 12.148 might be a very effective drug for the treatment of hypercholesterolemia."
01/01/1994 - "Lifibrol, a new drug for the treatment of hypercholesterolemia, contains a stereogenic center bearing a secondary alcohol group. "
01/01/1995 - "Lifibrol is a potent lipid-lowering drug in patients with hypercholesterolemia."
01/01/1995 - "To determine the effects of lifibrol on serum lipids in adult patients with primary hypercholesterolemia. "
01/01/1995 - "Lifibrol: a novel lipid-lowering drug for the therapy of hypercholesterolemia. "

05/01/2000 - "Kinetic studies were performed in five male hypercholesterolemic individuals (type IIa), before and on treatment with 450 mg of Lifibrol daily for 4 weeks and in five male individuals suffering from mixed hyperlipidemia (type IIb), before and on therapy, for 12 weeks. "
05/01/1999 - "Kinetic studies were performed in four male hypercholesterolemic individuals (type IIa) before and on treatment with 450 mg of Lifibrol daily for 4 weeks, and in five male individuals suffering from mixed hyperlipidemia (type IIb) before and on therapy for 12 weeks. "
05/01/2000 - "HDL steady state levels are not affected, but HDL apoA-I turnover is enhanced by Lifibrol in patients with hypercholesterolemia and mixed hyperlipidemia."
05/01/1999 - "Lifibrol enhances the low density lipoprotein apolipoprotein B-100 turnover in patients with hypercholesterolemia and mixed hyperlipidemia."

05/01/2000 - "We examined the impact of Lifibrol on the metabolism of HDL apoA-I in patients with hyperlipoproteinemia, using endogenous labeling with stable isotopes. "
05/01/1999 - "The impact of Lifibrol on the metabolism of apoB-100 containing lipoproteins in patients with hyperlipoproteinemia using endogenous labeling with stable isotopes is examined. "

01/01/1990 - "The application of lifibrol had no significant influence on the weight gain of the pigs and did not alter the serum levels of AST and ALT. "

11/01/2000 - "In the hepatoma cell line HepG2, Lifibrol decreased the formation of sterols from [14C]-acetic acid by approximately 25%. "