Bradykinin

A nonapeptide messenger that is enzymatically produced from KALLIDIN in the blood where it is a potent but short-lived agent of arteriolar dilation and increased capillary permeability. Bradykinin is also released from MAST CELLS during asthma attacks, from gut walls as a gastrointestinal vasodilator, from damaged tissues as a pain signal, and may be a neurotransmitter.

Also Known As:

Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg; Bradykinin Acetate, (9-D-Arg)-Isomer; Bradykinin Diacetate; Bradykinin Hydrochloride; Bradykinin Triacetate; Bradykinin, (1-D-Arg)-Isomer; Bradykinin, (2-D-Pro)-Isomer; Bradykinin, (2-D-Pro-3-D-Pro-7-D-Pro)-Isomer; Bradykinin, (2-D-Pro-7-D-Pro)-Isomer; Bradykinin, (3-D-Pro)-Isomer; Bradykinin, (3-D-Pro-7-D-Pro)-Isomer; Bradykinin, (5-D-Phe)-Isomer; Bradykinin, (5-D-Phe-8-D-Phe)-Isomer; Bradykinin, (6-D-Ser)-Isomer; Bradykinin, (7-D-Pro)-Isomer; Bradykinin, (8-D-Phe)-Isomer; Bradykinin, (9-D-Arg)-Isomer; Arg Pro Pro Gly Phe Ser Pro Phe Arg

Pharmalogical Action Categories:

Vasodilator Agents

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Intercellular Signaling Peptides and Proteins: 29768
    - Kinins: 2029
      - Bradykinin: 3860
  - Nerve Tissue Proteins: 2
    - Neuropeptides: 6772
      - Bradykinin: 3860
- Peptides: 82426
  - Intercellular Signaling Peptides and Proteins: 29768
    - Kinins: 2029
      - Bradykinin: 3860
  - Neuropeptides: 6772
    - Bradykinin: 3860
  - Oligopeptides: 519
    - Bradykinin: 3860
Biological Factors: 2472
- Intercellular Signaling Peptides and Proteins: 29768
  - Kinins: 2029
    - Bradykinin: 3860
- Inflammation Mediators: 1113
  - Autacoids: 276
    - Kinins: 2029
      - Bradykinin: 3860

Phe(8)-psi-CH2NH-Arg(9)- bradykinin

Bio-Agent Context: Research Results