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1- (2- nitro- 1- imidazoyl)- 3- (2,2,2- trifluoroethoxy)- 2- propanol

Also Known As:

TF-MISO

Networked: 2 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Nitro Compounds: 66
  - Nitroimidazoles: 565
    - Misonidazole: 539
      - 1-(2-nitro-1-imidazoyl)-3-(2,2,2-trifluoroethoxy)-2-propanol: 2
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Imidazoles: 150
      - Nitroimidazoles: 565
        Misonidazole: 539
        1-(2-nitro-1-imidazoyl)-3-(2,2,2-trifluoroethoxy)-2-propanol: 2

Experts

1.	Burgman, Paul: 1 article (06/2007)
2.	Chapman, J Donald: 1 article (06/2007)
3.	Claus, Filip: 1 article (06/2007)
4.	Koutcher, Jason A: 1 article (06/2007)
5.	Koziorowski, Jacek: 1 article (06/2007)
6.	Ling, C Clifton: 1 article (06/2007)
7.	Matei, Cornelia: 1 article (06/2007)
8.	Procissi, Daniel: 1 article (06/2007)
9.	Thakur, Sunitha B: 1 article (06/2007)

Related Diseases

1.	Neoplasms (Cancer) 06/15/2007 - "The feasibility of obtaining TF-MISO tumor distribution maps in a reasonable time frame was established. " 06/15/2007 - "Late time point (>6 h) tumor tissue concentrations, as obtained from (19)F MRS, suggest that TF-MISO is reduced and retained in hypoxic tumor. " 04/01/1992 - "Photobiological studies were performed with EMT-6 tumor cells in vitro utilizing Photofrin II (PII) in combination with etanidazole (ETAN), misonidazole (MISO), and trifluoromisonidazole (TF-MISO). " 06/15/2007 - "2-Nitro-alpha-[(2,2,2-trifluoroethoxy)methyl]-imidazole-1-ethanol (TF-MISO) was investigated as a potential noninvasive marker of tissue oxygen levels in tumors using (19)F magnetic resonance spectroscopy (MRS) and (19)F chemical shift imaging. "
2.	Hypoxia (Hypoxemia) 06/15/2007 - "Based on the results presented herein, it is suggested that TF-MISO has the potential to be a valid magnetic resonance hypoxia imaging reporter for both preclinical hypoxia studies and hypoxia-directed clinical therapy."

Related Drugs and Biologics

1.	Etanidazole
2.	Dihematoporphyrin Ether (Porfimer Sodium)
3.	Misonidazole
4.	Oxygen (Dioxygen)
5.	Ethanol (Ethyl Alcohol)
6.	imidazole

Related Therapies and Procedures

1.	Therapeutics