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geniposidic acid

from Gardenia fructus (zhi-zi); RN given refers to (1S-(1alpha,4aalpha,7aalpha))-isomer

Networked: 19 relevant articles (2 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Chen, Hao: 3 articles (06/2019 - 02/2016)
2.	Zhao, Wei: 3 articles (06/2019 - 02/2016)
3.	Liu, Changhui: 2 articles (08/2022 - 02/2016)
4.	Mi, Suiqing: 2 articles (06/2019 - 02/2016)
5.	Wang, Ningsheng: 2 articles (06/2019 - 02/2016)
6.	Yu, Hao: 2 articles (06/2019 - 02/2019)
7.	Fu, Hui: 1 article (12/2022)
8.	Zhu, Hui: 1 article (12/2022)
9.	Cai, Mingxiang: 1 article (08/2022)
10.	Cui, Yi: 1 article (08/2022)

Related Diseases

1.	Osteoporosis 01/01/2023 - "Geniposidic acid (GPA), one of the active components of Eucommia ulmoides, promote bone formation and treat osteoporosis by activating farnesoid X receptor (FXR). " 11/01/2003 - "Methanol extract (MeOH), n-hexane (Hx), chloroform (CHCl3), ethyl acetate (EA), butanol (BuOH) and aqueous (H2O) fractions of Eucommiae Cortex including geniposidic acid (GA), geniposide (GP) and aucubin (AU) were tested for their therapeutic efficacy on osteoporosis. "
2.	Memory Disorders (Memory Loss) 02/15/2020 - "Geniposidic acid ameliorates spatial learning and memory deficits and alleviates neuroinflammation via inhibiting HMGB-1 and downregulating TLR4/2 signaling pathway in APP/PS1 mice."
3.	Neuroinflammatory Diseases 02/15/2020 - "Geniposidic acid ameliorates spatial learning and memory deficits and alleviates neuroinflammation via inhibiting HMGB-1 and downregulating TLR4/2 signaling pathway in APP/PS1 mice."
4.	Stroke (Strokes) 06/01/2014 - "To establish a UPLC-MS/MS method for the simultaneous determination of geniposide, genipin 1-O-beta-D-gentiobioside and geniposidic acid in rat brains and study the brain pharmacokinetics of the three iridoid glycosides in stroke rat after the oral administration of Xingnaojing. "
5.	Squamous Cell Carcinoma of Head and Neck 12/01/2022 - "The present study aimed to investigate the potential effects of three iridoids genipin, geniposide and geniposidic acid on three human oral squamous cell carcinoma (OSCC) cell lines HSC-2, SCC-9 and A253 in addition to studying the possible underlying mechanisms. "

Related Drugs and Biologics

1.	geniposide
2.	Chloroform (Trichloromethane)
3.	Butanols (Butyl Alcohols)
4.	Methanol (Carbinol)
5.	n-hexane
6.	ethyl acetate
7.	aucubin
8.	genipin
9.	Iridoids
10.	Iridoid Glycosides

Related Therapies and Procedures

1.	Oral Administration