SRS-A

A group of LEUKOTRIENES; (LTC4; LTD4; and LTE4) that is the major mediator of BRONCHOCONSTRICTION; HYPERSENSITIVITY; and other allergic reactions. Earlier studies described a "slow-reacting substance of ANAPHYLAXIS" released from lung by cobra venom or after anaphylactic shock. The relationship between SRS-A leukotrienes was established by UV which showed the presence of the conjugated triene. (From Merck Index, 11th ed)

Also Known As:

Slow Reacting Substance of Anaphylaxis

Lipids: 114793
- Fatty Acids: 27405
  - Unsaturated Fatty Acids: 8236
    - Eicosanoids: 3262
      - Arachidonic Acids: 122
        Leukotrienes: 4095
        SRS-A: 186
    - Essential Fatty Acids: 734
      - Arachidonic Acids: 122
        Leukotrienes: 4095
        SRS-A: 186
Biological Factors: 2472
- Inflammation Mediators: 1113
  - Autacoids: 276
    - Eicosanoids: 3262
      - Leukotrienes: 4095
        SRS-A: 186

18- carboxy- 19,20- dinor- N- acetylleukotriene E4

Bio-Agent Context: Research Results