HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

fibrolase

from the venom of Agkistrodon contortrix; direct-acting fibrin-degrading zinc-metalloproteinase; MW 23-25kDa; cleaves primarily the Aa-chain of human fibrinogen & fibrin between the Lys-413 & Leu-414 position; the Bb chain is cleaved more slowly; gamma chain is minimally affected
Also Known As:
Agkistrodon contortrix fibrin-degrading metalloprotease
Networked: 8 relevant articles (2 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Markland, F S: 2 articles (12/2004 - 12/2000)
2. Swenson, S: 2 articles (12/2004 - 12/2000)
3. Markland, Francis S: 1 article (01/2010)
4. Swenson, Steve: 1 article (01/2010)
5. Johansson, J: 1 article (12/2004)
6. Pena, L: 1 article (12/2004)
7. Toombs, C F: 1 article (12/2004)
8. Bush, L R: 1 article (12/2000)

Related Diseases

1. Thrombosis (Thrombus)
2. Hemorrhage
3. Stroke (Strokes)
4. Venous Thrombosis (Deep-Vein Thrombosis)
5. Carotid Artery Thrombosis

Related Drugs and Biologics

1. Fibrin
2. Enzymes
3. Venoms
4. Metalloproteases (Metalloproteinases)
5. Anistreplase (APSAC)
6. Peptides (Polypeptides)
7. Recombinant DNA (Recombinant DNA Research)
8. alfimeprase
9. arginyl-glycyl-aspartic acid

Related Therapies and Procedures

1. Catheters