HOME
PRODUCTS
COMPANY
CONTACT
FAQ
Research
Dictionary
Pharma
Sign Up
FREE
or
Login
Username:
Password:
Remember login
Login
Send password reminder...
pentamorphone
Also Known As:
RX 77989; RX-77989; RX77989; n-pentylaminomorphinone; Morphinan-6-one, 7,8-didehydro-4,5-epoxy-3-hydroxy-17-methyl-14-(pentylamino)-, (5alpha)-
Networked:
4
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
Alkaloids: 5398
Opiate Alkaloids: 5944
Morphinans: 33
Morphine Derivatives: 39
Hydromorphone: 766
pentamorphone: 4
Bridged-Ring Heterocyclic Compounds
Morphinans: 33
Morphine Derivatives: 39
Hydromorphone: 766
pentamorphone: 4
Fused-Ring Heterocyclic Compounds
4 or More Rings Heterocyclic Compounds
Morphinans: 33
Morphine Derivatives: 39
Hydromorphone: 766
pentamorphone: 4
Polycyclic Compounds: 6
Polycyclic Aromatic Hydrocarbons: 2020
Phenanthrenes: 27
Morphinans: 33
Morphine Derivatives: 39
Hydromorphone: 766
pentamorphone: 4
Related Diseases
1.
Pain (Aches)
05/01/1991 - "
Only patients given 0.24 micrograms/kg of pentamorphone experienced decreased pain intensity and increased sedation, both transient in duration.
"
03/01/1989 - "
Pentamorphone produced a linear increase in pain tolerance with increasing dose as well as a dose-dependent depression of ventilation.
"
2.
Postoperative Pain
05/01/1991 - "
Pentamorphone (0.08-0.24 micrograms/kg) was ineffective for treating acute postoperative pain after major surgery.
"
05/01/1991 - "
Pentamorphone for management of postoperative pain.
"
05/01/1991 - "
The efficacy, duration, and safety of the synthetic opioid pentamorphone in the treatment of acute postoperative pain were evaluated in a randomized, double-blind study of 72 patients given 0.08, 0.16, or 0.24 micrograms/kg of pentamorphone or a placebo intravenously in the recovery room after major abdominal or orthopedic surgery.
"
3.
Hypotension (Low Blood Pressure)
04/01/1992 - "
When pentamorphone is used as the sole IV anesthetic in lorazepam-premedicated patients with normal or mildly impaired ventricular function, there is a high incidence of hypotension during induction, and poor control of hemodynamic responses to stimulation.
"
4.
Hypertension (High Blood Pressure)
04/01/1992 - "
Despite additional pentamorphone (total dose 9.6 +/- 1.8 micrograms/kg), 6 patients required thiopental and/or enflurane to control hypertension intraoperatively.
"
5.
Hypercapnia
10/01/1990 - "
Pentamorphone produced dose-related reductions in the ventilatory responses to both hypercapnia and hypoxia.
"
10/01/1990 - "
We quantified the effects of pentamorphone (0.08, 0.24, and 0.60 micrograms/kg, IV) on ventilatory responses to hypercapnia and hypoxia in 12 healthy volunteers.
"
10/01/1990 - "
Depression of ventilatory responses to hypoxia and hypercapnia after pentamorphone.
"
Related Drugs and Biologics
1.
Thiopental (Pentothal)
2.
Lorazepam (Ativan)
3.
Enflurane (Ethrane)
4.
Anesthetics (Anesthetic Agents)
5.
Opioid Analgesics (Opioids)
Related Therapies and Procedures
1.
Orthopedic Procedures