coronatine

consists of a coronafacic acid joined by an amide bond to coronamic acid by coronafacate ligase; phytotoxin produced by Pseudomonas syringae; RN given refers to (3aS-(3aalpha,4(1R*,2R*),6beta,7alpha))-isomer;

Networked: 63 relevant articles (1 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Duan, Liusheng: 4 articles (01/2020 - 03/2008)
2.	He, Sheng Yang: 3 articles (11/2015 - 07/2010)
3.	Uppalapati, Srinivasa Rao: 3 articles (01/2011 - 01/2009)
4.	Zhou, Yuyi: 2 articles (01/2020 - 05/2019)
5.	Dodo, Kosuke: 2 articles (01/2018 - 05/2017)
6.	Egoshi, Syusuke: 2 articles (01/2018 - 05/2017)
7.	Ishimaru, Yasuhiro: 2 articles (01/2018 - 05/2017)
8.	Sodeoka, Mikiko: 2 articles (01/2018 - 05/2017)
9.	Takaoka, Yousuke: 2 articles (01/2018 - 05/2017)
10.	Ueda, Minoru: 2 articles (01/2018 - 05/2017)

Related Diseases

1.	Infections 07/01/2022 - "Null msl10-1 mutants were delayed in PR1 induction and displayed modest susceptibility to infection by coronatine-deficient P. " 12/07/2020 - "The loss-of-function in JA signalling mediated by the JA-insensitive coronatine-insensitive 1 (coi1) mutant impaired the hyper-induction of defense gene expression and promoted pathogen proliferation in MS-treated plants subject to infection. " 01/01/2017 - "However, coronatine produced by Pseudomonas syringae pv. tomato (Pst) DC3000 cells can open dark-closed stomata facilitating infection. " 01/01/2016 - "Coronatine Facilitates Pseudomonas syringae Infection of Arabidopsis Leaves at Night." 10/01/2014 - "In contrast, a dip inoculation assay revealed that RCAR3-overexpression mutants inhibited stomatal reopening during Pst DC3000 infection and coronatine (COR) treatment, leading to enhanced resistance to Pst DC3000, which was not accompanied by differential expression of PR1 and NPR1 genes. "
2.	Melanoma (Melanoma, Malignant) 01/01/2019 - "In this study, we evaluated the inhibitory effect of coronatine (COR) on the proliferation of metastatic melanoma cells. " 01/01/2019 - "Metabolic and lipidomic investigation of the antiproliferative effects of coronatine against human melanoma cells."
3.	Growth Disorders 11/01/2020 - "In this study, we show that herbivory-induced stunted growth of Nicotiana attenuata was completely dependent on allene oxide cyclase (AOC) and coronatine insensitive1 (COI1), which encode a JA biosynthetic enzyme and the receptor, respectively, but only partially dependent on jasmonic acid-isoleucine conjugate (JA-Ile), the bioactive jasmonate. "
4.	Hypochromic Anemia (Chlorosis) 05/01/2021 - "Coronatine (COR) is a non-host specific phytotoxin secreted by Pseudomonas syringae pv. tomato that can induce leaf chlorosis and increase the virulence of pathogens during plant-pathogen interactions. " 04/01/2016 - "By comparing the activity of inducibly expressed AvrRpm1-HA or AvrRpt2-HA in rpm1rps2 and rpm1rps2coi1 backgrounds, we demonstrate that both effectors promote bacterial growth dependent on a COI1-mediated pathway and additively with the action of coronatine (COR) and that AvrRpt2-HA induces COI1-dependent chlorosis. " 01/01/2014 - "Coronatine (COR) is a chlorosis-inducing non-host-specific phytotoxin that induces leaf and/or fruit abscission in some crops. " 01/01/2013 - "Pseudomonas syringae pv. tomato DC3000 produces the phytotoxin coronatine, a major determinant of the leaf chlorosis associated with DC3000 pathogenesis. " 12/01/2011 - "brassicicola, or coronatine (COR), a bacterial phytotoxin that promotes chlorosis. "
5.	Wounds and Injuries (Trauma) 02/01/2001 - "These results indicated that coronatine mimicked the wound response but was insufficient to activate JA-regulated PR genes." 10/01/2019 - "12-Hydroxy-Jasmonoyl-l-Isoleucine Is an Active Jasmonate That Signals through CORONATINE INSENSITIVE 1 and Contributes to the Wound Response in Arabidopsis." 06/01/2014 - "Wound-induced expression of DEFECTIVE IN ANTHER DEHISCENCE1 and DAD1-like lipase genes is mediated by both CORONATINE INSENSITIVE1-dependent and independent pathways in Arabidopsis thaliana." 05/01/2000 - "Analysis of the coronatine-insensitive coi1-1 Arabidopsis mutant that is also insensitive to jasmonate allowed us to identify a large number of COI1-dependent and COI1-independent wound-inducible genes. " 02/01/2001 - "The induction of tomato leucine aminopeptidase genes (LapA) after Pseudomonas syringae pv. tomato infection is primarily a wound response triggered by coronatine."

Related Drugs and Biologics

1.	jasmonic acid (jasmonate)
2.	Salicylic Acid (2 Hydroxybenzoic Acid)
3.	Isoleucine (L-Isoleucine)
4.	Enzymes
5.	jasmonoyl-isoleucine
6.	hydroperoxide isomerase (allene oxide cyclase)
7.	1-amino-2-ethylcyclopropane-1-carboxylic acid
8.	Proteins (Proteins, Gene)
9.	coronafacic acid
10.	Amino Acids