HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

meglumine cyclic adenylate

Networked: 6 relevant articles (1 outcomes, 3 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Chen, Jing-Li: 1 article (06/2017)
2.	Liu, Henry: 1 article (06/2017)
3.	Liu, Wei: 1 article (06/2017)
4.	Yan, Hong: 1 article (06/2017)
5.	Guo, Limin: 1 article (09/2014)
6.	Li, Weiqiang: 1 article (09/2014)
7.	Liao, Jingwu: 1 article (09/2014)
8.	Lin, Daqiang: 1 article (09/2014)
9.	Lu, Ning: 1 article (09/2014)
10.	Pu, Bo: 1 article (09/2014)

Related Diseases

1.	Post-Traumatic Stress Disorders (Post Traumatic Stress Disorder) 01/01/2023 - "Single activation of PKA by systemic application of rolipram (ROL) or meglumine cyclic adenylate (M-cAMP) before re-exposure promoted fear extinction and improved anxiety-like behavior in PTSD mice. "
2.	Spinal Cord Injuries (Spinal Cord Injury) 01/01/2023 - "Meglumine cyclic adenylate improves cardiovascular hemodynamics and motor-function in a rat model of acute T4 thoracic spinal cord injury." 09/01/2014 - "Meglumine cyclic adenylate improves neurological function following acute spinal cord injury in rats." 09/01/2014 - "The present study examined the effects of meglumine cyclic adenylate (MCA) on neurological recovery, cAMP concentration, adenylate cyclase 3 (AC3) activity and phosphodiesterase 4D (PDE4D) activity during early stage acute spinal cord injury (SCI) in rats. "
3.	Inflammation (Inflammations) 06/01/2017 - "This study was to investigate the effects of pretreatment with meglumine cyclic adenylate (MCA), a compound of meglumine and cAMP, on systemic inflammation induced by lipopolysaccharide (LPS) in rats. "
4.	Brain Ischemia (Cerebral Ischemia) 01/01/2023 - "Pretreatment with meglumine cyclic adenylate not only significantly ameliorated neuron loss in CA1 region after global cerebral ischemia but also enhanced STAT3-Ser727 phosphorylation, increased mitochondrial STAT3, and decreased cytosolic Cyt c and active caspase-3. " 01/01/2023 - "Male Sprague-Dawley rats were subjected to 15 min global cerebral ischemia, and meglumine cyclic adenylate was treated through tail intravenous injection 30 min before ischemia. " 01/01/2023 - "The present study aims to investigate the neuroprotective effect of meglumine cyclic adenylate, an activator of PKA, under a rat model of global cerebral ischemia/reperfusion and to reveal the underlying mechanism involving signal transducer and activator of transcription 3 (STAT3)-Ser727 phosphorylation and mitochondrion modulation. "
5.	Systemic Inflammatory Response Syndrome (Sepsis Syndrome) 06/01/2017 - "Effects of meglumine cyclic adenylate pretreatment on systemic inflammatory response syndrome induced by lipopolysaccharide in rats."

Related Drugs and Biologics

1.	Rolipram
2.	Type 4 Cyclic Nucleotide Phosphodiesterases
3.	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)
4.	Neuroprotective Agents
5.	Meglumine
6.	Lipopolysaccharides
7.	adenylate cyclase 3
8.	Caspase 3 (Caspase-3)

Related Therapies and Procedures

1.	Intravenous Injections