NKY 722

RN given refers to dihydrochloride; RN for parent cpd not available 2/89

Also Known As:

1,4-dihydro 2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 2,2-dimethyl-3-(4-(2-propenyl)-1-piperazinyl)propyl methyl ester; NKY-722

Networked: 2 relevant articles (1 outcomes, 0 trials/studies)

1.	Wounds and Injuries (Trauma) 02/01/1994 - "NKY-722 improved the renal dysfunction, and reduced glomerular, renal and cerebral arterial injuries in Dahl-S rats. " 02/01/1994 - "The effect of NKY-722 on glomerulosclerosis and arterial injuries is, at least partly, independent of blood pressure, and is probably related to the effect on eicosanoid metabolism." 02/01/1994 - "Protective effect of the calcium antagonist NKY-722 against renal and arterial injuries in Dahl salt-sensitive rats."
2.	Atrioventricular Block 03/01/1989 - "In AV node preparations, NKY-722 prolonged AV conduction time and produced second- or third-degree AV block in large doses only when administered into the artery supplying the AV node. "