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parathyroid hormone (7-34)

Also Known As:

PTH (7-34); bPTH (7-34); bovine parathyroid hormone (7-34)

Networked: 8 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Hormones, Hormone Substitutes, and Hormone Antagonists
- Hormones: 80400
  - Peptide Hormones: 1347
    - Parathyroid Hormone: 11951
      - parathyroid hormone (7-34): 8
Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Peptide Hormones: 1347
    - Parathyroid Hormone: 11951
      - parathyroid hormone (7-34): 8
  - Peptide Fragments: 373
    - parathyroid hormone (7-34): 8

Related Diseases

1.	Neoplasms (Cancer) 08/01/1996 - "Based on these and related studies, the antagonist [Nle8,18,D-Trp12,Tyr34]bPTH(7-34)NH2 has displayed sufficient potency to obtain approval from the appropriate institutional and regulatory agencies for clinical trials in hypercalcemic states of parathyroid and tumor origin." 01/01/1988 - "The similarity in biological profiles despite structural differences between hHCF and PTH is emphasized by the inhibitory action of [Tyr-34]bPTH-(7-34)NH2 against the tumor peptide even in the absence of much of the homologous region in the PTH antagonist. "
2.	Hypercalcemia (Milk Alkali Syndrome) 05/01/1994 - "In the present studies, the PTH antagonists [Tyr34]bovine (b) PTH-(7-34)NH2, [D-Trp12,Tyr34]-bPTH-(7-34)NH2, or PTHrP-(7-34)NH2, were administered to hypercalcemic athymic nude mice bearing a human squamous cell carcinoma of the lung in 60- to 500-fold molar excess of a dose of PTHrP-(1-34) known to produce hypercalcemia. "
3.	Squamous Cell Carcinoma (Epidermoid Carcinoma) 05/01/1994 - "In the present studies, the PTH antagonists [Tyr34]bovine (b) PTH-(7-34)NH2, [D-Trp12,Tyr34]-bPTH-(7-34)NH2, or PTHrP-(7-34)NH2, were administered to hypercalcemic athymic nude mice bearing a human squamous cell carcinoma of the lung in 60- to 500-fold molar excess of a dose of PTHrP-(1-34) known to produce hypercalcemia. "
4.	Bone Resorption 09/01/1984 - "The PTH antagonists [8,18norleucine, 34tyrosine]bovine PTH (3-34) amide and [34tyrosine]bovine PTH (7-34) completely inhibited PTH-stimulated bone resorption. " 02/01/1987 - "Neither [8Nle,18Nle,34Tyr]bovine (b) PTH-(3-34) amide nor [34Tyr]bPTH-(7-34)amide inhibited bone resorption or limb bone cAMP accumulation induced by either processed conditioned medium or equivalent concentrations of bPTH-(1-34). "
5.	Wounds and Injuries (Trauma) 05/01/1999 - "Topical application of parathyroid hormone related protein (1-36) or parathyroid hormone (7-34) did not result in significant changes in the healing rate and morphology of the wounds. " 05/01/1999 - "To define better the role of parathyroid hormone-related protein in the skin, we investigated the spatial and temporal expression of parathyroid hormone-related protein and mRNA by immunohistochemistry and in situ hybridization during the healing of skin wounds, and the effects of topical administration of a parathyroid hormone-related protein agonist [parathyroid hormone-related protein (1-36)] and a parathyroid hormone-related protein antagonist [parathyroid hormone (7-34)] on the healing rate and morphology of the wounds. "

Related Drugs and Biologics

1.	Amides
2.	Parathyroid Hormone-Related Protein
3.	Conditioned Culture Media
4.	Messenger RNA (mRNA)
5.	Peptides (Polypeptides)
6.	Parathyroid Hormone (Parathormone)

Related Therapies and Procedures

1.	Topical Administration