cortifen

Russian drug; complex ester of 11-deoxy-17-hydroxycorticosterone & chlorphenacyl

Also Known As:

corticosterone 11-deoxy-17alpha-hydroxy-21-(N-di-(2-chloroethyl)aminophenyl acetate); cortiphen; kortifen

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Bogdanova, L A: 1 article (10/2016)
2.	Kaledin, V I: 1 article (10/2016)
3.	Morozkova, T S: 1 article (10/2016)
4.	Nikolin, V P: 1 article (10/2016)
5.	Popova, N A: 1 article (10/2016)
6.	Tornuev, Yu V: 1 article (10/2016)

Related Diseases

1.	Neoplasms (Cancer) 01/01/1990 - "The antitumour activity of cortiphen synthesized at the All-Union Cancer Research Centre of the USSR Academy of Medical Sciences was studied on human tumour strains transplanted into nude mice and rats. " 01/01/1990 - "[Effects of cortiphen on human tumor strains transplanted into athymic mice and rats]." 01/01/1989 - "Practically all the tumors were shown to respond to cortiphen action. " 10/01/2016 - "Liposomal and free cortifen (hydrophobic hormonal cytostatic) produced nearly the same effects on solid tumor growth. " 01/01/1989 - "Cortiphen was found to interact with glucocorticoid receptors in both animal and human tumors. "
2.	Sarcoma (Soft Tissue Sarcoma) 01/01/1990 - "Two strains of colon adenocarcinoma out of three have displayed an expressed sensitivity to cortiphen, while melanoma and Jewing sarcoma strains proved to be weakly sensitive to the preparation." 01/01/1990 - "Cortiphen and cyclophosphamide were studied for their effect on the mixed uterus sarcoma induced primarily by 1,2-dimethylhydrazine and oestradiol-dipropionate in CBA mice and its transplants. " 01/01/1990 - "[Effects of cortiphen and cyclophosphamide in uterine sarcoma induced primarily by 1,2-dimethylhydrazine and estradiol dipropionate in CBA mice]."
3.	Melanoma (Melanoma, Malignant) 01/01/1990 - "Two strains of colon adenocarcinoma out of three have displayed an expressed sensitivity to cortiphen, while melanoma and Jewing sarcoma strains proved to be weakly sensitive to the preparation."
4.	Kidney Neoplasms (Kidney Cancer) 01/01/1990 - "Cortiphen was found to possess an expressed activity to kidney cancer, cancer of corpus uteri, chorionepithelioma, fibrosarcoma. "
5.	Fibrosarcoma 01/01/1990 - "Cortiphen was found to possess an expressed activity to kidney cancer, cancer of corpus uteri, chorionepithelioma, fibrosarcoma. "

Related Drugs and Biologics

1.	Cytostatic Agents
2.	Glucocorticoid Receptors (Glucocorticoid Receptor)
3.	1,2-Dimethylhydrazine (1,2 Dimethylhydrazine)
4.	Estradiol (Delestrogen)
5.	Cyclophosphamide (Cytoxan)
6.	Antineoplastic Agents (Antineoplastics)
7.	estradiol dipropionate