1,4-dideoxy-1,4-iminoarabinitol

RN given refers to (2S-(2alpha,3beta,4alpha))-isomer; structure given in first source

Also Known As:

1,4-dideoxy-1,4-imino-D-arabinitol; 1,4-dideoxy-1,4-imino-L-arabinitol; 1,4-dideoxy-1,4-iminoarabinitol, (2R-(2alpha,3beta,4alpha))-isomer; 1,4-dideoxy-1,4-iminoarabinitol, (2R-(2alpha,3beta,4beta))-isomer; 1,4-dideoxy-1,4-iminoarabinitol, (2S-(2alpha,3beta,4beta))-isomer; 1,4-dideoxy-1,4-iminoribitol; 2-hydroxymethylpyrrolidine-3,4-diol

Networked: 3 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Adachi, Isao: 1 article (01/2016)
2.	Fleet, George W J: 1 article (01/2016)
3.	Hirono, Shuichi: 1 article (01/2016)
4.	Imahori, Tatsushi: 1 article (01/2016)
5.	Kato, Atsushi: 1 article (01/2016)
6.	Nakagome, Izumi: 1 article (01/2016)
7.	Nash, Robert J: 1 article (01/2016)
8.	Natori, Yoshihiro: 1 article (01/2016)
9.	Sato, Kasumi: 1 article (01/2016)
10.	Takahata, Hiroki: 1 article (01/2016)

Related Diseases

1.	Neuroinflammatory Diseases 09/01/2022 - "In the present study, we determined whether the glycogen phosphorylase(GP)inhibitor 1,4-dideoxy-1,4-imino-D-arabinitol (DAB) ameliorates pentylenetetrazole (PTZ)-induced acute seizure, neuroinflammation and memory impairment in rats. "
2.	Gaucher Disease (Gaucher's Disease) 01/21/2016 - "We report on the synthesis and biological evaluation of a series of α-1-C-alkylated 1,4-dideoxy-1,4-imino-d-arabinitol (DAB) derivatives as pharmacological chaperones for Gaucher disease. "
3.	Hypoxia (Hypoxemia) 04/01/2015 - "Hypoxia-induced activation of rostral ventrolateral medulla oblongata neurons was suppressed in the presence of either an ATP receptor antagonist MRS2179 or a glycogenolysis inhibitor 1,4-dideoxy-1,4-imino-d-arabinitol, suggesting that sensitivity of these neurons to low PO2 is mediated by actions of extracellular ATP and lactate. "

Related Drugs and Biologics

1.	Glycogen Phosphorylase (Phosphorylase, Glycogen)
2.	Pentylenetetrazole (Metrazol)
3.	Lactic Acid (Lactate)
4.	Purinergic P2 Receptors (ADP Receptor)
5.	Adenosine Triphosphate (ATP)
6.	N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate