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aridanin

from aridan (tetrapleura tetraptera); RN given from CAS Index Guide

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Triterpenes: 2493
      - Pentacyclic Triterpenes: 108
        Oleanolic Acid: 547
        aridanin: 3
      - Sapogenins: 26
        Oleanolic Acid: 547
        aridanin: 3

Experts

1.	Akinmoladun, Afolabi C: 1 article (01/2021)
2.	Bhagat, Reshma: 1 article (01/2021)
3.	Ojo, Olubukola Benedicta: 1 article (01/2021)
4.	Olaleye, M Tolulope: 1 article (01/2021)
5.	Rema, Velayudhan: 1 article (01/2021)
6.	Saliu, Ibrahim Olabayode: 1 article (01/2021)
7.	Seth, Pankaj: 1 article (01/2021)
8.	Abdelfatah, Sara: 1 article (06/2020)
9.	Bonsou, Idrios N: 1 article (06/2020)
10.	Chi, Godloves F: 1 article (06/2020)

Related Diseases

1.	Neurodegenerative Diseases (Neurodegenerative Disease) 01/01/2021 - "Aridanin, naringenin, ferulic acid, and scopoletin demonstrated good binding affinities with hGS indicating that Tetrapleura tetraptera is a potential source of new plant-based bioactives relevant in the therapy of neurodegenerative diseases."
2.	Schistosomiasis (Bilharziasis) 02/01/1991 - "The results predict a poor action of aridanin as an ovicidal agent in the control of snail intermediate hosts of schistosomiasis."
3.	Neoplasms (Cancer) 06/08/2020 - "Aridanin and doxorubicin (positive control) inhibited the proliferation of all cancer cell lines tested. " 06/08/2020 - "N-acetylglycoside of oleanolic acid (aridanin) displays promising cytotoxicity towards human and animal cancer cells, inducing apoptotic, ferroptotic and necroptotic cell death." 06/08/2020 - "We evaluated the cytotoxic potential of a naturally occurring N-acetylglycoside of oleanolic acid, aridanin, on 18 cancer cell lines, including sensitive and drug-resistant phenotypes mediated by P-glycoprotein, BCRP, p53 knockout, deletion-mutated EGFR, or BRAF mutations. "
4.	Melanoma (Melanoma, Malignant) 06/08/2020 - "Aridanin had considerably lower IC50 values than that of doxorubicin against multidrug-resistant CEM/ADR5000 cells and melanoma cell lines (MaMel-80a, Mel-2a, MV3, and SKMel-505). "

Related Drugs and Biologics

1.	Member 1 Subfamily B ATP Binding Cassette Transporter
2.	Scopoletin
3.	Oleanolic Acid
4.	Doxorubicin (Adriamycin)
5.	naringenin
6.	ferulic acid (sodium ferulate)

Related Therapies and Procedures

1.	Therapeutics