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1,4-butanediol diisethionate
structure given in first source
Also Known As:
1,4-BIT
Networked:
2
relevant articles (
1
outcomes,
0
trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Organic Chemicals: 133
Hydrocarbons: 1713
Acyclic Hydrocarbons
Alkanes: 241
Alkanesulfonic Acids
Alkanesulfonates: 9
Mesylates: 334
Busulfan: 2106
1,4-butanediol diisethionate: 2
Alcohols: 595
Glycols: 38
Butylene Glycols: 2
Busulfan: 2106
1,4-butanediol diisethionate: 2
Sulfur Compounds: 278
Sulfur Acids
Sulfonic Acids: 1605
Alkanesulfonic Acids
Alkanesulfonates: 9
Mesylates: 334
Busulfan: 2106
1,4-butanediol diisethionate: 2
Related Diseases
1.
Sarcoma (Soft Tissue Sarcoma)
09/01/1988 - "
Although a program of five daily ip treatments with busulfan was not effective in treating sarcoma 180-bearing mice, a fluorine-containing busulfan analog, 1,4-butanediol di-2,2,2-trifluoroethanesulfonate (BFS), and a water-soluble analog, 1,4-butanediol diisethionate (BIT), were significantly effective when given on the same schedule.
"
2.
Sarcoma 180
12/01/1981 - "
In order to determine the effectiveness of isethionates as anticancer alkylating agents, 1,4-butanediol diisethionate was prepared as a model compound and its anticancer activities against adenocarcinoma 755, sarcoma 180, L1210, and P388 were compared with those of the corresponding methanesulfonate, busulfan.
"
3.
Adenocarcinoma
12/01/1981 - "
In order to determine the effectiveness of isethionates as anticancer alkylating agents, 1,4-butanediol diisethionate was prepared as a model compound and its anticancer activities against adenocarcinoma 755, sarcoma 180, L1210, and P388 were compared with those of the corresponding methanesulfonate, busulfan.
"
Related Drugs and Biologics
1.
Busulfan (Busulfex)
2.
Fluorine
3.
1,4-butanediol di-2,2,2-trifluoroethanesulfonate
4.
Alkylating Agents
5.
methanesulfonic acid (methanesulfonate)