HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

1,4-butanediol diisethionate

structure given in first source

Also Known As:

1,4-BIT

Networked: 2 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Related Diseases

1.	Sarcoma (Soft Tissue Sarcoma) 09/01/1988 - "Although a program of five daily ip treatments with busulfan was not effective in treating sarcoma 180-bearing mice, a fluorine-containing busulfan analog, 1,4-butanediol di-2,2,2-trifluoroethanesulfonate (BFS), and a water-soluble analog, 1,4-butanediol diisethionate (BIT), were significantly effective when given on the same schedule. "
2.	Sarcoma 180 12/01/1981 - "In order to determine the effectiveness of isethionates as anticancer alkylating agents, 1,4-butanediol diisethionate was prepared as a model compound and its anticancer activities against adenocarcinoma 755, sarcoma 180, L1210, and P388 were compared with those of the corresponding methanesulfonate, busulfan. "
3.	Adenocarcinoma 12/01/1981 - "In order to determine the effectiveness of isethionates as anticancer alkylating agents, 1,4-butanediol diisethionate was prepared as a model compound and its anticancer activities against adenocarcinoma 755, sarcoma 180, L1210, and P388 were compared with those of the corresponding methanesulfonate, busulfan. "

Related Drugs and Biologics

1.	Busulfan (Busulfex)
2.	Fluorine
3.	1,4-butanediol di-2,2,2-trifluoroethanesulfonate
4.	Alkylating Agents
5.	methanesulfonic acid (methanesulfonate)