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clavulone II

coral prostanoids from Clavularia viridis; see also record for clavulones

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Lipids: 114793
- Fatty Acids: 27405
  - Unsaturated Fatty Acids: 8236
    - Eicosanoids: 3262
      - Prostaglandins: 17100
        Prostaglandins A: 1719
        clavulone II: 3
Biological Factors: 2472
- Inflammation Mediators: 1113
  - Autacoids: 276
    - Eicosanoids: 3262
      - Prostaglandins: 17100
        Prostaglandins A: 1719
        clavulone II: 3

Experts

1.	Guh, Jih-Hwa: 1 article (01/2005)
2.	Huang, Yu-Chun: 1 article (01/2005)
3.	Shen, Ya-Ching: 1 article (01/2005)
4.	Teng, Che-Ming: 1 article (01/2005)

Related Diseases

1.	Acute Promyelocytic Leukemia 01/01/2005 - "In the present study, we illustrate the pathways utilized by clavulone II to trigger apoptotic signaling in human acute promyelocytic leukemia HL-60 cells. " 01/01/2005 - "Investigation of anticancer mechanism of clavulone II, a coral cyclopentenone prostaglandin analog, in human acute promyelocytic leukemia."
2.	Vesicular Stomatitis 12/01/1991 - "Antiviral activity of the prostanoid clavulone II against vesicular stomatitis virus."
3.	Mitochondrial Diseases (Mitochondrial Disease) 01/01/2005 - "Exposure of cells to clavulone II resulted in early induction of phosphatidylserine externalization, mitochondrial dysfunction, and alteration of the cell cycle. "
4.	Sarcoma 180 09/01/1988 - "Daily treatment with lipo-chlorovulone I (1.6 mg/kg/day, i.p.) and lipo-clavulone II (12.5 mg/kg/day, i.p.) on days 1 through 5 markedly prolonged the survival time (135% ILS and 73% ILS, respectively) of mice inoculated with sarcoma 180 as compared with that of a corresponding dose of respective free chlorovulone I and clavulone II. These results suggest that lipid microspheres may be used as drug delivery carriers for antitumor coral prostanoids in vivo."

Related Drugs and Biologics

1.	Prostaglandins
2.	Synthetic Prostaglandins (Prostaglandin Analogues)
3.	Phosphatidylserines
4.	Lipids
5.	Antiviral Agents (Antivirals)
6.	chlorovulone I
7.	cyclopentenone

Related Therapies and Procedures

1.	Microspheres (Microsphere)