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Cloturin

structure given in first source

Also Known As:

6-(N-(2-chloroethyl)carbamoyl)thiopurine; VUFB 15686; VUFB-15686; cloturine

Networked: 4 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Halogenated Hydrocarbons: 42
    - Mustard Compounds: 3
      - Cloturin: 4
- Sulfur Compounds: 278
  - Sulfhydryl Compounds: 4168
    - Mercaptopurine: 1822
      - Cloturin: 4
Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Purines: 651
      - Mercaptopurine: 1822
        Cloturin: 4

Related Diseases

1.	Carcinoma (Carcinomatosis) 06/01/1992 - "The main purpose of the present investigation was to study the effect of cloturin on aerobic glycolysis, endogenous and exogenous respiration and the level of ATP in both Ehrlich ascites carcinoma (EAC) and P388 murine leukaemia cells incubated in vitro. " 01/01/1988 - "The effect of cloturin on biosynthesis of DNA, RNA and proteins in both P388 and Ehrlich ascites carcinoma (EAC) cells have been studied in vitro. "
2.	Ascites 06/01/1992 - "Cloturin: effect on energy-producing processes in Ehrlich ascites and P388 murine leukaemia cells." 01/01/1988 - "Inhibition of biosynthetic processes in P388 and Ehrlich ascites cells by cloturin." 06/01/1992 - "The main purpose of the present investigation was to study the effect of cloturin on aerobic glycolysis, endogenous and exogenous respiration and the level of ATP in both Ehrlich ascites carcinoma (EAC) and P388 murine leukaemia cells incubated in vitro. " 01/01/1988 - "The effect of cloturin on biosynthesis of DNA, RNA and proteins in both P388 and Ehrlich ascites carcinoma (EAC) cells have been studied in vitro. "
3.	Neoplasms (Cancer) 01/01/1989 - "The cancerostatic effect of 6-purinyl-N-(2-chloroethyl)thiocarbamate (Cloturin VUFB, VUFB-15686) was studied in detail in mice and rats bearing transplantable tumors. "
4.	Leukopenia 01/01/1991 - "Cloturin decreased cellularity of spleen and bone marrow, elicited leukocytopenia in peripheral blood, suppressed phagocytosis, graft-versus-host reaction and specific antibody production. "

Related Drugs and Biologics

1.	Adenosine Triphosphate (ATP)
2.	Cloturin
3.	RNA (Ribonucleic Acid)
4.	Proteins (Proteins, Gene)
5.	DNA (Deoxyribonucleic Acid)