4- chloro- 3',6'- dimethyl- 2,2'- iminodibenzoate (TO 115)

03/01/1977 - "Drug treatment has been shown to significantly reduce morbidity and mortality in patients with diastolic blood pressures above 104 mm Hg. Evidence suggests that drug treatment is also effective in those with diastolic pressures between 90 and 104 mm Hg. Selection of drugs is still an empirical decision--treatment with an oral diuretic usually is effective for mild hypertension (diastolic pressures 90 to 115 mm Hg). "
08/01/1990 - "Forty-four patients with essential hypertension of mild (n = 40) or moderate (n = 4) severity (90 less than DBP less than or equal to 115 mmHg at the end of the placebo period) entered and completed the single-blind, placebo-controlled trial. "
02/26/1986 - "Forty-three patients with mild to moderate hypertension (supine diastolic blood pressure 95 to 115 mm Hg) were entered into a short-term (3 months) study. "
04/24/2007 - "Corresponding thresholds for normal ABP were 123.9/76.8, 129.9/82.6, and 110.2/68.1 mm Hg, respectively, and those for ambulatory hypertension were 131.0/79.4, 138.2/86.4, and 119.5/70.8 mm Hg. After rounding, approximate thresholds for optimal ABP amounted to 115/75 mm Hg for 24 hours, 120/80 mm Hg for daytime, and 100/65 mm Hg for nighttime. "
06/01/1997 - "One week of intravenous Ang II infusion produced hypertension (mean arterial pressure from 80 +/- 2 up to 115 +/- 8 mm Hg), with significantly increased heart rate and hematocrit. "

12/01/1998 - "Effects of losartan and amlodipine on blood pressure and albuminuria were compared in a randomized, double-blind, parallel trial involving 48 patients with essential hypertension (sitting diastolic blood pressure between 95 to 115 mm Hg) and impaired renal function (creatinine clearance of 30 to 60 ml/min/1.73 m2). "

06/01/2004 - "The programs were administered to 115 chronic pain patients recruited from a hospital-based pain management program and 115 age- and gender-matched healthy individuals without pain. "
01/01/1999 - "The Brief Pain Inventory--Short Form (BPI-SF) was administered along with the Short-Form McGill Pain Questionnaire (SF-MPQ) and two visual analogue scales, one for pain while at rest (VAS-R) and one for pain upon movement (VAS-M), in random order, to 115 hospitalized patients twice following their surgery. "
01/01/1994 - "Ninety-six migraineurs were compared to 115 normal subjects, 36 neurotics, 38 psychosomatic patients, 52 patients suffering from other pain disorders and 38 unipolar depressives, matched for sex, age and social status. "
05/01/1991 - "A patient was classified as having hip OA if pain was present in combination with either 1) hip internal rotation greater than or equal to 15 degrees, pain present on internal rotation of the hip, morning stiffness of the hip for less than or equal to 60 minutes, and age greater than 50 years, or 2) hip internal rotation less than 15 degrees and an erythrocyte sedimentation rate (ESR) less than or equal to 45 mm/hour; if no ESR was obtained, hip flexion less than or equal to 115 degrees was substituted (sensitivity 86%; specificity 75%). "
08/01/1990 - "Ten to 15 min following epidural application of 70 to 115 mg bupivacaine (mean = 99 mg), peak plasma concentrations occurred (mean = 0.41 micrograms/ml) The maximum plasma level of 0.7 micrograms/ml bupivacaine was found in a patient who had received epidural anesthesia for pain relief during labor. "

09/01/2000 - "The mean arc of flexion improved from 7 degrees (range, 0 to 30 degrees) preoperatively to 67 degrees (range, 10 to 115 degrees) after the surgery. "
06/05/2013 - "The mean arc of flexion also significantly increased, from 60.3° to 115.6° (p < 0.01). "
03/01/2000 - "The arc of motion averaged 56 degrees (range, 30 to 75 degrees) preoperatively and 89 degrees (range, 65 to 115 degrees) at the time of follow-up. "
03/01/1999 - "The mean range of active flexion in 24 knees was 97 degrees (78 to 115) and the mean arc of movement 91 degrees (78 to 98). "
07/01/1998 - "Of the 68 ankylosed elbows, 59 (87%) regained a mean arc of painless movement of 88.5 degrees (27 to 115). "

06/01/2014 - "The partial pressure of arterial oxygenation increased significantly from baseline values of 55 +/- 10 to 115 +/- 31 mm Hg during supplementation from the oxygen concentrator, to 138 +/- 21 mm Hg during supplementation from the oxygen cylinder at 1 L/min, and to 201 +/- 42 mm Hg at 2 L/min. In conclusion, low flow rates of intranasal oxygen supplemented continuously from an oxygen cylinder or by pulsed delivery from a portable oxygen concentrator effectively treated hypoxemia in anesthetized white-tailed deer."
10/01/2000 - "During hemodilution, hypercapnia, and hypoxia with a plasma viscosity of 1. 0 cP, CBF varied from 98 to 115 ml. 100 g(-1). "
05/01/1990 - "Rats were exposed for 2 h either to 115 dB SPL noise, to 5% oxygen in nitrogen (hypoxia) or to both hypoxia and noise. "
09/01/1996 - "Hypoxia was induced in eight subjects who inspired a mixture of nitrogen and oxygen through a gas blender adjusted to reduce the partial pressure of oxygen from (mean +/- SE) 98 +/- 4 to 48 +/- 1 mm Hg. During normoxia, L-NMMA increased systemic vascular resistance from 1,108 +/- 74 to 1,705 +/- 87 dynes-s-cm-5 and increased pulmonary vascular resistance from 60 +/- 5 to 115 +/- 9 dynes-s-cm-5 (p < or = 0.01 for each). "