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litoxetine

a serotonin uptake inhibitor

Also Known As:

4-(2-naphthalenylmethoxy)piperidine; SL 81-0385; SL-81035

Networked: 2 relevant articles (1 outcomes, 0 trials/studies)

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Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Piperidines: 17
    - litoxetine: 2

Experts

1.	Dmochowski, Roger R: 1 article (01/2021)
2.	Haab, Francois: 1 article (01/2021)
3.	Robinson, Dudley: 1 article (01/2021)

Related Diseases

1.	Urinary Incontinence 01/01/2021 - "A randomized, placebo-controlled clinical development program exploring the use of litoxetine for treating urinary incontinence." 01/01/2021 - "To investigate the safety and efficacy of litoxetine, a serotonin reuptake inhibitor, in treating urinary incontinence (UI) and mixed urinary incontinence (MUI). "
2.	Vomiting 03/02/1993 - "If nausea and vomiting associated with the use of 5 HT uptake inhibitors are due to stimulation of 5HT3 receptors, the concomitant 5HT3 antagonism of litoxetine may limit the gastrointestinal side-effects of this novel antidepressant and thus offer an important advantage." 03/02/1993 - "Litoxetine (at 1 and 10 mg/kg i.v.) dose dependently reduced the number of retches and vomiting as well as the number of emetic episodes induced by cisplatin (10 mg/kg i.v.) and delayed the onset of emesis. "
3.	Nausea 03/02/1993 - "If nausea and vomiting associated with the use of 5 HT uptake inhibitors are due to stimulation of 5HT3 receptors, the concomitant 5HT3 antagonism of litoxetine may limit the gastrointestinal side-effects of this novel antidepressant and thus offer an important advantage."

Related Drugs and Biologics

1.	Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)
2.	Emetics
3.	Cisplatin (Platino)
4.	Antidepressive Agents (Antidepressants)