Ro 21-5104

structure given in first source; main metabolite of mefloquine

Also Known As:

2,8-MMQ; 2,8-bis(trifluoromethyl)-4-quinolinecarboxylic acid; Ro-21-5104; carboxymefloquine; mefloquine carboxylic acid

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

1.	D'Alessandro, Umberto: 1 article (09/2014)
2.	Davies, Geraint R: 1 article (09/2014)
3.	Lindegardh, Niklas: 1 article (09/2014)
4.	Tarning, Joel: 1 article (09/2014)
5.	Tinto, Halidou: 1 article (09/2014)
6.	Toe, Laeticia C: 1 article (09/2014)
7.	Traore-Coulibaly, Maminata: 1 article (09/2014)
8.	Valea, Innocent: 1 article (09/2014)
9.	Van Geertruyden, Jean-Pierre: 1 article (09/2014)
10.	Ward, Stephen A: 1 article (09/2014)

1.	Malaria 09/01/2014 - "This study was conducted to assess the pharmacokinetic properties of mefloquine/carboxymefloquine and artesunate/dihydroartemisinin in pregnant and non-pregnant women with uncomplicated malaria. "
2.	Vomiting 02/01/2007 - "Predictors of RII/RIII parasitologic response were vomiting after MQ dosing, Day 2 MQ levels < 500 ng/mL, and undetectable Day 2 levels of the carboxymefloquine metabolite. "

1.	Mefloquine (Lariam)
2.	Artesunate
3.	artenimol (dihydroartemisinin)