neuromedin U

01/01/2020 - "Neuromedin U (NMU) activates two receptors (NMUR1 and NMUR2) and is a promising candidate for development of drugs to combat obesity. "
08/28/2015 - "Small lipidated anti-obesity compounds derived from neuromedin U."
08/01/2012 - "PEGylation of Neuromedin U yields a promising candidate for the treatment of obesity and diabetes."
09/12/2007 - "Sensitivity of the hypothalamic paraventricular nucleus to the locomotor-activating effects of neuromedin U in obesity."
08/01/2005 - "These data establish neuromedin U as a target in obesity."

10/27/2022 - "Neuromedin U-deficient rats do not lose body weight or food intake."
11/01/2014 - "Central neuromedin U 2 receptor (NMU2R) plays important roles in the regulation of food intake and body weight. "
09/01/2009 - "To investigate the role of the central neuromedin U (NMU) signaling system in body weight and energy balance regulation, we examined the effects of long-term intracerebroventricular (icv) infusion of NMU in C57Bl/6 mice and in mice lacking the gene encoding NMU receptor 2. In diet-induced obese male and female C57BL/6 mice, icv infusion of NMU (8 microg x day(-1) x mouse(-1)) for 7 days decreased body weight and total energy intake compared with vehicle treatment. "
08/14/2006 - "Neuromedin U 2 receptor (NMU2R) plays important roles for the regulation of food intake and body weight. "
08/01/2005 - "Transgenic mice overexpressing neuromedin U have lower body weight, less somatic and liver fat, were hypophagic, and had improved insulin sensitivity. "

08/01/2005 - "Transgenic mice overexpressing neuromedin U have lower body weight, less somatic and liver fat, were hypophagic, and had improved insulin sensitivity. "

01/01/2022 - "Evidence from studies of cell lines and animals implies that neuromedin U (NmU) acts as a pro-inflammatory mediator of type 2 inflammation. "
01/01/2021 - "Neuromedin U: potential roles in immunity and inflammation."
05/01/2008 - "Neuromedin U inhibits inflammation-mediated memory impairment and neuronal cell-death in rodents."
08/01/2007 - "Neuromedin U (NMU) has recently been reported to have a role in nociception and inflammation. "
02/01/2020 - "Effect of neuromedin U on allergic airway inflammation in an asthma model."

01/01/2021 - "Accumulating evidence shows that the aberrant expression of neuromedin U (NMU) contributes to the initiation and progression of cancer. "
09/30/2019 - "Analysis of different pancreatic cancer databases showed that Neuromedin U (NMU) expression was positively correlated with YAP1 expression in the tumor group. "
05/30/2017 - "Neuromedin U (NMU) has been shown driving the progression of various tumor entities, including breast cancer. "
01/20/2020 - "Erratum: Neuromedin U: A Small Peptide in the Big World of Cancer. "
09/05/2019 - "Neuromedin U: A Small Peptide in the Big World of Cancer."