Goe 5438

structure given in first source

Also Known As:

Goe-5438; NC-1500; ethyl 1,4-dihydro-5-isopropoxy-2-methyl-4-(2-trifluoromethylphenyl)-1,6-naphthyridine-3-carboxylate; 1,6-Naphthyridine-3-carboxylic acid, 1,4-dihydro-2-methyl-5-(1-methylethoxy)-4-(2-(trifluoromethyl)phenyl)-, ethyl ester, (+-)-

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Naphthyridines: 2
      - Goe 5438: 1

Experts

1.	Jeong, S Y: 1 article (08/2001)
2.	Kobayashi, T: 1 article (08/2001)
3.	Okamoto, T: 1 article (08/2001)

Related Diseases

1.	Hepatitis 08/01/2001 - "The effect of NC-1500 on mice concanavalin A-induced hepatitis was examined. " 08/01/2001 - "The present results showed that NC-1500 inhibited Con A-induced hepatitis without affecting TNF-alpha mRNA expression in the liver." 08/01/2001 - "NC-1500 prevents concanavalin A-induced mice hepatitis without affecting cytokine gene expression."

Related Drugs and Biologics

1.	Cytokines
2.	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
3.	Messenger RNA (mRNA)
4.	Concanavalin A