hemoglobin Geneva

change in codon 114 from CTG(Leu) to -GG that results in a frameshift and the presumed synthesis of an abnormal beta chain that is 156 residues long with a completely different C-terminal amino acid sequence

Also Known As:

Hb Geneva

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Blood Proteins: 12459
    - Hemoglobins: 37188
      - Abnormal Hemoglobins: 120
        hemoglobin Geneva: 2
  - Hemeproteins: 194
    - Globins: 2716
      - Hemoglobins: 37188
        Abnormal Hemoglobins: 120
        hemoglobin Geneva: 2

Experts

1.	Pugin, P: 1 article (08/2001)
2.	Salathé, C: 1 article (08/2001)

Related Diseases

1.	Myeloid Sarcoma (Chloroma) 08/01/2001 - "[Extramedullary hematopoiesis presenting as a chloroma in a patient known for abnormal hemoglobin (Geneva hemoglobin)]."
2.	beta-Thalassemia (Cooley's Anemia) 08/01/1988 - "Inclusion body beta-thalassemia trait in a Swiss family is caused by an abnormal hemoglobin (Geneva) with an altered and extended beta chain carboxy-terminus due to a modification in codon beta 114."

Related Drugs and Biologics

1.	Hemoglobins (Hemoglobin)
2.	Codon (Codons)