HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

soyasaponin I

from roots of Gypsophila sp.; dominant saponin found in most legumes

Networked: 12 relevant articles (1 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Triterpenes: 2493
      - Pentacyclic Triterpenes: 108
        Oleanolic Acid: 547
        soyasaponin I: 12
      - Sapogenins: 26
        Oleanolic Acid: 547
        soyasaponin I: 12
Carbohydrates: 22023
- Glycosides: 2119
  - Saponins: 2867
    - soyasaponin I: 12

Experts

1.	Wang, Peng-Hui: 3 articles (04/2017 - 02/2005)
2.	Chang, Wei-Wei: 2 articles (03/2006 - 02/2005)
3.	Lin, Tzu-Wen: 2 articles (03/2006 - 02/2005)
4.	Tsai, Ying-Chieh: 2 articles (03/2006 - 02/2005)
5.	Chou, Yu-Ting: 1 article (04/2017)
6.	Hsieh, Shie-Liang: 1 article (04/2017)
7.	Lee, Oscar Kuang-Sheng: 1 article (04/2017)
8.	Sung, Pi-Lin: 1 article (04/2017)
9.	Wen, Kuo-Chang: 1 article (04/2017)
10.	Wu, Cheng-Wen: 1 article (04/2017)

Related Diseases

1.	Neuroblastoma 01/01/2016 - "Protection against 1-methyl-4-phenyl pyridinium-induced neurotoxicity in human neuroblastoma SH-SY5Y cells by Soyasaponin I by the activation of the phosphoinositide 3-kinase/AKT/GSK3β pathway."
2.	Neoplasms (Cancer) 04/25/2017 - "Inhibition of ST3GalI using a competitive inhibitor, Soyasaponin I (SsaI), inhibited tumor cell migration and dissemination in the in vivo mouse model with transplanted MOSEC cells. " 08/10/2009 - "Soyasaponin extracts, aglycones of group A and B and individual group B soyasaponins such as soyasaponin I have been reported to posses specific bioactive properties, such as in vitro anti-cancer properties by modulating the cell cycle and inducing apoptosis. " 03/10/2006 - "In this study, we evaluated the effects of soyasaponin I (Ssa I), a known inhibitor of STs, on tumor metastasis through studying a highly metastatic cancer cell line B16F10. " 02/01/2005 - "Soyasaponin-I-modified invasive behavior of cancer by changing cell surface sialic acids." 12/01/1992 - "Afromosin [1] and soyasaponin I [2] isolated from Wistaria brachybotrys exhibited remarkable inhibitory effects on mouse skin tumor promotion, and afromosin also exhibited a significant inhibitory effect on pulmonary tumor promotion. "
3.	Colonic Neoplasms (Colon Cancer) 07/08/2022 - "Anti-Colon Cancer Activity of Dietary Phytochemical Soyasaponin I and the Induction of Metabolic Shifts in HCT116." 01/01/2003 - "In this study, therefore, purified soyasaponins and soyasapogenins were tested for their ability to suppress the growth of HT-29 colon cancer cells, as determined by the WST-1 assay, over a concentration range of 0-50 ppm. Soyasaponin I and III, soyasapogenol B monoglucuronide, soyasapogenol B, soyasaponin A1, soyasaponin A2, and soyasapogenol A were evaluated. "
4.	Neoplasm Metastasis (Metastasis) 03/10/2006 - "In this study, we evaluated the effects of soyasaponin I (Ssa I), a known inhibitor of STs, on tumor metastasis through studying a highly metastatic cancer cell line B16F10. "
5.	Hypertensive Intracranial Hemorrhage 12/31/2023 - "Soyasaponin I alleviates hypertensive intracerebral hemorrhage by inhibiting the renin-angiotensin-aldosterone system."

Related Drugs and Biologics

1.	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)
2.	soyasapogenol B
3.	soyasapogenol A
4.	Phytochemicals
5.	N-Acetylneuraminic Acid (Sialic Acid)
6.	Sialic Acids
7.	Saponins
8.	Complement System Proteins (Complement)
9.	sophoradiol
10.	kaikasaponin III