HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

benzo(a)pyrene-DNA adduct

structure given in first source

Also Known As:

BaP-DNA adduct; DNA-benzo(a)pyrene adduct

Networked: 9 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Cherng, Shur-Hueih: 1 article (03/2006)
2.	Hsu, Shih-Lan: 1 article (03/2006)
3.	Lee, Huei: 1 article (03/2006)
4.	Yang, Jia-Ling: 1 article (03/2006)
5.	Yu, Chang-Tze Ricky: 1 article (03/2006)
6.	Kang, Se Chan: 1 article (11/2005)
7.	Lee, Byung Mu: 1 article (11/2005)
8.	Chang, Xiaoqing: 1 article (05/2002)
9.	Maier, Andrew: 1 article (05/2002)
10.	Puga, Alvaro: 1 article (05/2002)

Related Diseases

1.	Hepatocellular Carcinoma (Hepatoma) 05/27/2002 - "We find that exposure of mouse hepatoma Hepa-1 cells to low concentrations of arsenite increases BaP-DNA adduct levels by as much as 18-fold. " 03/01/2006 - "In this study, our data showed that benzo[a]pyrene (BaP)-DNA adduct levels were decreased in a dose-dependent manner when the human hepatoma cell line HepG2 simultaneously treated with BaP and 1-nitropyrene (1-NP). "
2.	Carcinogenesis 01/01/2001 - "DNA adduct formation is thought to initiate carcinogenesis, so the effect of BghiP on BaP-DNA adduct formation was evaluated using a (32)P-postlabeling assay. " 01/01/1989 - "Benzo[a]pyrene (BaP)/DNA adduct formation appears to be involved in carcinogenesis, but the relationship between adduct formation and BaP-induced immunotoxicity is unknown. " 09/01/1984 - "Benzo(a)pyrene-DNA adduct formation and removal in mouse epidermis in vivo and in vitro: relationship of DNA binding to initiation of skin carcinogenesis." 11/12/2005 - "To investigate the role of estrogen and estrogen receptor (ER) during benzo[a]pyrene (BaP) carcinogenesis, BaP-DNA adduct formation, and DNA synthesis were examined in ER-positive, MCF-7, and ER-negative, MDA-MB-231, human breast cancer cell lines. "
3.	Breast Neoplasms (Breast Cancer) 06/01/1986 - "Benzo(a)pyrene:DNA adduct formation in normal human mammary epithelial cell cultures and the human mammary carcinoma T47D cell line." 11/12/2005 - "Effect of estrogen receptor (ER) on benzo[a]pyrene-DNA adduct formation in human breast cancer cells." 11/12/2005 - "To investigate the role of estrogen and estrogen receptor (ER) during benzo[a]pyrene (BaP) carcinogenesis, BaP-DNA adduct formation, and DNA synthesis were examined in ER-positive, MCF-7, and ER-negative, MDA-MB-231, human breast cancer cell lines. "
4.	Contact Dermatitis (Eczema, Contact) 06/25/1999 - "Data suggest that the expression of the genes responsible for the differences in responsiveness to chemical induced contact dermatitis in mouse may play an important role in benzo[a]pyrene-DNA adduct formation." 06/25/1999 - "Comparison of benzo[a]pyrene DNA adduct formation in the skin of two strains of mice selected for resistance (DBA/2) or susceptibility (C3H/HeN) to contact dermatitis."
5.	Adenoma (Adenomas) 06/01/1999 - "Metabolic proficiency and benzo[a]pyrene DNA adduct formation in APCMin mouse adenomas and uninvolved mucosa."

Related Drugs and Biologics

1.	Benzo(a)pyrene
2.	1-nitropyrene
3.	DNA (Deoxyribonucleic Acid)
4.	DNA Adducts
5.	Estrogen Receptors
6.	Estrogens (Estrogen)
7.	arsenite