icariin

10/15/2016 - "Icariin (ICA), the major constituent of Epimedium brevicornu Maxim, is recognized as an effective agent for the treatment of osteoporosis. "
01/01/2012 - "Icariin (ICA) is an active component of Herba Epimedium effective in preventing osteoporosis. "
01/01/2020 - "Together, these findings indicate that icariin exerts its anti-osteoporotic function by inhibiting JNK/c-Jun signaling pathway, and suggest that icariin may be a promising treatment option for osteoporosis."
01/01/2023 - "Osteoporosis remission via an anti-inflammaging effect by icariin activated autophagy."
11/30/2017 - "Therefore, a systematic review and meta-analysis was performed to evaluate the efficacy of icariin against osteoporosis in ovariectomized rats. "

12/01/2018 - "This study aimed to explore the pharmacological effects of icariin in IDD by simulating NP inflammation in vitro. "
09/04/2023 - ": Our findings suggest that icariin treatment can alleviate the development of RA by reducing cell proliferation and inflammation in RA-FLS through the regulation of the GAREM1/MAPK signaling pathway. "
01/01/2023 - "Icariin alleviates autistic-like behavior, hippocampal inflammation and vGlut1 expression in adult BTBR mice."
09/01/2022 - "Moreover, in vivo experimental results revealed that icariin restored inflammation and deterioration in RA mice by upregulating TRIB1. "
06/25/2022 - "Icariin (ICA) is a small molecule drug capable of promoting cartilage repair and ameliorating inflammation. "

01/01/2023 - "Icariin (ICA), an active ingredient extracted from Epimedium species, has shown promising results in the treatment of Alzheimer's disease (AD), although its potential therapeutic mechanism remains largely unknown. "
01/25/2010 - "The present study was undertaken to investigate the protective effects of icariin on the learning and memory abilities in Alzheimer's disease model rats and explore its protection mechanisms. "
04/01/2022 - "Icariin Ameliorates Alzheimer's Disease Pathology by Alleviating Myelin Injury in 3 × Tg-AD Mice."
01/25/2010 - "All tests indicated icariin improved the ability of spatial learning and memory in Alzheimer's disease model rats. "
01/01/2023 - "In this study, we investigated the neuroprotective mechanism of icariin in an APP/PS1/Tau triple-transgenic mouse model of Alzheimer's disease. "

01/01/2021 - "Icariin improved diabetes, renal function, restored autophagy, and alleviated fibrosis in type 2 diabetic neuropathic rats and in vitro. "
01/01/2021 - "Icariin Ameliorates Diabetic Renal Tubulointerstitial Fibrosis by Restoring Autophagy via Regulation of the miR-192-5p/GLP-1R Pathway."
01/01/2022 - "In this study, we aimed to investigate the impact of GPER on renal fibrosis and whether icariin attenuates renal fibrosis dependent on GPER. "
11/01/2021 - "This study aimed to determine the effects of icariin on renal fibrosis and explore its molecular mechanisms. "
06/01/2019 - "The aims of this study were to investigate whether icariin treatment improves the development of CKD-associated renal fibrosis and its possible mechanism. "

01/01/2018 - "A 24-month randomized double-blind placebo-controlled clinical trial reported that icariin was effective in preventing postmenopausal osteoporosis with relatively low side effects. "
10/01/2016 - "Our objective was to summarize and critically assess the bone mass improved effect of icariin (ICA) for treatment of postmenopausal osteoporosis in an OVX-induced rat model. "
05/01/2017 - "The present findings indicate that icariin has potential as a novel alternative therapeutic agent for fracture healing in postmenopausal osteoporosis."
09/01/2014 - "To explore this question, we tested the effects of icariin on bone mineral density (BMD) and marrow fat content in a rat model of postmenopausal osteoporosis. "
05/01/2012 - "Icariin associated with exercise therapy is an effective treatment for postmenopausal osteoporosis."