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leiurotoxin I

3.4kDa peptide from Leiurus quinquestriatus hebraeus venom; potent apamin binding inhibitor; amino acid sequence given in first source

Also Known As:

scyllatoxin

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Complex Mixtures: 1906
- Venoms: 4328
  - Arthropod Venoms: 770
    - Scorpion Venoms: 373
      - leiurotoxin I: 2
Biological Factors: 2472
- Biological Toxins: 20
  - Venoms: 4328
    - Arthropod Venoms: 770
      - Scorpion Venoms: 373
        leiurotoxin I: 2

Related Diseases

1.	Pheochromocytoma 12/25/1992 - "Characterization and partial purification from pheochromocytoma cells of an endogenous equivalent of scyllatoxin, a scorpion toxin which blocks small conductance Ca(2+)-activated K+ channels."
2.	Neuroblastoma 07/22/1991 - "Characterization and regulation of the expression of scyllatoxin (Leiurotoxin I) receptors in the human neuroblastoma cell line NB-OK 1." 07/22/1991 - "125I-[Tyr2]scyllatoxin allowed to label a single class of high-affinity receptors in membranes from the human neuroblastoma cell line NB-OK 1. The Kd of these receptors was 60 pM for scyllatoxin (Leiurotoxin I) and 20 pM for apamin and the Bmax was low (3.8 fmol/mg membrane protein). "

Related Drugs and Biologics

1.	leiurotoxin I
2.	Scorpion Venoms (Scorpion Venom)
3.	Membrane Proteins (Integral Membrane Proteins)
4.	Apamin
5.	scyllatoxin receptor