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prolinamide

RN given refers to cpd without isomeric designation

Also Known As:

2-pyrrolidinecarboxamide; prolinamide, (L)-isomer

Networked: 19 relevant articles (1 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Amino Acids: 30675
  - Cyclic Amino Acids: 3
    - Imino Acids: 11
      - Proline: 3391
        prolinamide: 19

Experts

1.	Ammazzalorso, Alessandra: 2 articles (01/2019 - 05/2018)
2.	Amoia, Pasquale: 2 articles (01/2019 - 05/2018)
3.	Amoroso, Rosa: 2 articles (01/2019 - 05/2018)
4.	Cataldi, Amelia: 2 articles (01/2019 - 05/2018)
5.	De Filippis, Barbara: 2 articles (01/2019 - 05/2018)
6.	Fantacuzzi, Marialuigia: 2 articles (01/2019 - 05/2018)
7.	Gallorini, Marialucia: 2 articles (01/2019 - 05/2018)
8.	Giampietro, Letizia: 2 articles (01/2019 - 05/2018)
9.	Maccallini, Cristina: 2 articles (01/2019 - 05/2018)
10.	Di Matteo, Mauro: 1 article (05/2018)

Related Diseases

1.	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 07/09/1983 - "Very high intravenous doses (2-19 mg/min) of thyrotropin-releasing hormone (TRH, L-pyroglutamyl-L-histidyl-L-prolinamide) given to 12 patients with amyotrophic lateral sclerosis (ALS) produced a moderate to marked improvement of functions caused by deficiency of lower motor neurons (weakness) and upper motor neurons (spasticity). "
2.	Neoplasms (Cancer) 06/28/2016 - "Further, in vitro cellular studies with human hepatocellular carcinoma (HepG2) cells indicate that the tris-prolinamide derivatives can inhibit cell proliferation and reduce c-MYC expression in cancer cells. "
3.	Hepatocellular Carcinoma (Hepatoma) 06/28/2016 - "Further, in vitro cellular studies with human hepatocellular carcinoma (HepG2) cells indicate that the tris-prolinamide derivatives can inhibit cell proliferation and reduce c-MYC expression in cancer cells. "
4.	Eosinophilia 12/01/1995 - "Therefore, in this study we examined the effects of two inhibitors of tryptase, APC 366 [N-(1-hydroxy-2-naphthoyl)-L-arginyl-L-prolinamide hydrochloride] and BABIM [bis(5-amidino-2-benzimidazolyl)methane] on antigen-induced early and late responses, airway responsiveness as measured by carbachol provocation, microvascular permeability as measured by bronchoalveolar lavage (BAL) albumin concentrations, and tissue eosinophilia from biopsies in allergic sheep. "
5.	Stroke (Strokes) 01/03/1991 - "The effects of YM-14673, a new thyroid-releasing hormone (TRH) analogue (N alpha-[[(S)-4-oxo-2-azetidinyl]carbonyl]-L-histidyl-L-prolinamide dihydrate), on neurological deficits were examined in stroke-prone spontaneously hypertensive rats (SHRSP). " 01/01/2000 - "To investigate the chronic effects of a novel thyrotropin-releasing hormone analog, JTP-2942 (N(alpha)-[(1S, 2R)-2-methyl-4-oxocyclopentylcarbonyl]-L-histidyl-L-prolinamide monohydrate), on behavioral changes after stroke, the authors examined its effects on motor and neurologic deficits using a middle cerebral artery (MCA) occlusion model in rats. "

Related Drugs and Biologics

1.	Thyrotropin-Releasing Hormone (Protirelin)
2.	Tryptases (Tryptase)
3.	Carbachol (Carbastat)
4.	Antigens
5.	Albumins
6.	N- (1- hydroxy- 2- naphthoyl)arginyl- prolinamide
7.	bis(5-amidino-2-benzimidazolyl)methane
8.	azetirelin
9.	Citric Acid (Citrate)
10.	TA 0910

Related Therapies and Procedures

1.	Therapeutics
2.	Induced Hypothermia
3.	Analgesia
4.	Oral Administration