N(3)- (4- methoxyfumaroyl)- 2,3- diaminopropionic acid

inhibits glucosamine synthetase in E coli; structure given in first source; RN given refers to (S-(E)-isomer)

Also Known As:

FMDP; N(3)-(4-methoxyfumaroyl)-2,3-diaminopropionic acid, R-(E)-isomer; N(3)-(4-methoxyfumaroyl)-L-2,3-diaminopropionic acid

Networked: 5 relevant articles (0 outcomes, 1 trials/studies)

1.	Andruszkiewicz, Ryszard: 1 article (01/2019)
2.	Coy, Emerson: 1 article (01/2019)
3.	Jurga, Stefan: 1 article (01/2019)
4.	Kertmen, Ahmet: 1 article (01/2019)
5.	Milewski, Sławomir: 1 article (01/2019)
6.	Popenda, Łukasz: 1 article (01/2019)
7.	Przysiecka, Łucja: 1 article (01/2019)
8.	Morguet, Andreas: 1 article (11/2007)
9.	Schwimmbeck, Peter L: 1 article (11/2007)
10.	Vallbracht-Israng, Katja B: 1 article (11/2007)

1.	Autolysis 05/01/1998 - "Results of the studies on consequences of GlcN-6-P isomerase inhibition upon the action of FMDP-dipeptides provided evidence demonstrating that the lack of endogenous GlcN-6-P could be a reason for the triggering of bacterial autolysis. "
2.	Lewis Lung Carcinoma 01/01/1991 - "However, FMDP-peptides do not exhibit any cytotoxicity against these cells, HeLa S3 human cervical carcinoma cells, and LL2 murine Lewis lung carcinoma cells. "
3.	Neoplasms (Cancer) 01/01/2019 - "It is shown that nanoparticle-mediated delivery transforms FMDP and BADP into strong anticancer agents by inhibiting the growth of the tested cancer cells, whereas their anti-Candidal activity is decreased. "
4.	Leukemia L1210 01/01/1991 - "Murine leukemia L1210 cells contain active glucosamine 6-phosphate synthase inhibited by N3-4-methoxyfumaroyl-L-2,3-diaminopropanoic acid (FMDP). "
5.	Inflammation (Inflammations) 11/01/2007 - "The underlying disease was myocardial inflammation (Inf) in 48 patients, in whom the mean (+/- SD) ENF of epicardial (FMDc-Inf 3.40+/-5.55%) and systemic (FMDp-Inf 3.69+/-2.93%) arteries was significantly impaired (P<0.001), compared with 13 control (Co) patients who had normal myocardial biopsies (FMDc-Co 14.51+/-8.62%; FMDp-Co 7.69+/-3.42%). "

1.	Dipeptides
2.	glucosamine 6-phosphate
3.	Isomerases
4.	Peptides (Polypeptides)
5.	Antineoplastic Agents (Antineoplastics)
6.	Acids
7.	norvalyl- N(3)- (4- methoxyfumaroyl)- 2,3- diaminopropionic acid