nitroguanidine

01/01/1984 - "In order to develop a model to study cytological alterations in human pancreatic cancer, we have exposed bovine pancreatic ductal organ explants to a single dose of 2.5 micrograms per ml of N-methyl-N-nitroso-N'- nitroguanidine (MNNG). "

01/01/1975 - "[Induction of stomach tumors in rats by N-methyl-N-nitroso-N1-nitroguanidine]."
03/15/1988 - "N-Methyl-N-nitro-N'-nitroguanidine treatment of BL6 melanoma cells was associated with an increase in class I H-2b Ag expression and NK sensitivity, suggesting the involvement of class I MHC Ag in the sensitivity of tumor cells to NK cell-mediated cytotoxicity."
09/01/1975 - "Gastric tumor induction by N-methyl-N-nitroso-N'-nitroguanidine and induction of tumors of the urinary bladder by N-[4-(5-nitro-2-furyl)-2thiazylyl]formamide were not influenced by diet. "
01/01/1983 - "The proliferation stimulating action of gastrin is also detectable at chronic oral application of N-Methyl-N'-nitroso-N-nitroguanidine for induction of stomach and intestinal tumors simultaneously to pentagastrin administration or partial stomach resection in the intact, tumor free oxyntic mucosa of stomach."
12/09/1976 - "The morphogenesis of neoplasms (carcinomas and pracecancerous polypoid lesions) induced by N-methyl-N-nitroso-N'-nitroguanidine (MNNG) was studied on 154 male Wistar rats (including controls), from which a group received a colostomy. "

01/01/2023 - "N-methyl-N-nitro-N-nitroguanidine (MNNG) is one of the main risk factors for gastric cancer. "
01/01/2023 - "The effect of phytochemicals in N-methyl-N-nitro-N-nitroguanidine promoting the occurrence and development of gastric cancer."
12/11/2022 - "N-methyl-N-nitro-N-nitroguanidine (MNNG) is one of the most important inducing factors of gastric cancer. "
03/01/2021 - "Modulatory effect of Tagetes erecta flowers essential oils via Nrf2/HO-1/NF-κB/p65 axis mediated suppression of N-methyl-N'nitro-N-nitroguanidine (MNNG) induced gastric cancer in rats."
03/01/2021 - "Protective effect of Tagetes erecta flowers essential oils was investigated on oxidative stress, immune response, inflammation, and apoptosis against N-methyl-N'nitro-N-nitroguanidine (MNNG) induced gastric cancer in rats. "

11/01/1992 - "The effect of natural carotenoids on gastric carcinogenesis induced by N-methyl-N'-nitro-N-nitroguanidine (MNNG) was studied in 4 groups containing 105 rats. "
09/01/1975 - "In further experiments, designed to examine the range of the dietary effect on chemical carcinogenesis, rats were fed either the marginally lipotrope-deficient, high-fat diet or an adequate control diet, and treated wit- N-2-fluorenylacet-amide, 3,3 diphenyl-3-diemthylcarbamoyl-1-propyne, N-methyl-N-nitroso-N'-nitroguanidine, N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide, aflatoxin G1, or ethionine. "
04/15/1996 - "The inhibitory effects of EGCG and green tea extract (GTE) on N-ethyl-N'-nitro-N-nitroguanidine (ENNG)-induced duodenal carcinogenesis in the mouse, N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced carcinogenesis of the glandular stomach in the rat, and azoxymethane-induced colon carcinogenesis in the rat were examined. "

01/01/1977 - "[Stomach adenocarcinoma induction in rats by the combined administration of N-methyl-N-nitroso-N'-nitroguanidine precursors]."
02/01/1975 - "Lung metastasis of canine gastric adenocarcinoma induced by N-methyl-N'-nitro-N-nitroguanidine."
01/01/1975 - "N-methyl-N-nitroso-N'-nitroguanidine was administered as drinking water to Wistar strain and non-inbred male rats in the dosage of 100 mKg/ml for 7 months, Adenocarcinomas of the stomach were produced in about 70% of rats. "