deoxyshikonin

01/01/2020 - "However, no studies are available to illustrate the effect of deoxyshikonin on acute myeloid leukemia (AML). "
01/01/2020 - "Deoxyshikonin Inhibits Viability and Glycolysis by Suppressing the Akt/mTOR Pathway in Acute Myeloid Leukemia Cells."

11/20/2018 - "Our results demonstrate that deoxyshikonin application promoted wound repair in STZ-induced diabetic mice. "
11/20/2018 - "An open skin wound was produced on the backs of diabetic mice and was then topically treated with deoxyshikonin or vehicle. "
03/06/2017 - "Moreover, 20µm deoxyshikonin-treated groups showed accelerated wound closure compared with the controls in a mouse model of cutaneous wounds. "
03/06/2017 - "The wound healing effects of deoxyshikonin was assessed in a mouse model of cutaneous wounds. "
01/01/2013 - "We also found that deoxyshikonin promoted wound healing in vitro by the induction of HMVEC-dLy migration into the wound gap. "

12/01/2019 - "Deoxyshikonin isolated from Arnebia euchroma inhibits colorectal cancer by down-regulating the PI3K/Akt/mTOR pathway."
01/01/2020 - "Deoxyshikonin was reported to exhibit an anti-tumor effect in colorectal cancer. "

06/26/2022 - "Deoxyshikonin Mediates Heme Oxygenase-1 Induction and Apoptotic Response via p38 Signaling in Tongue Cancer Cell Lines."

01/01/2023 - "These discoveries demonstrate that deoxyshikonin may be a possible chemotherapeutic candidate to induce cell arrest and apoptosis by activating extrinsic and intrinsic pathways through p38 for human osteosarcoma."
01/01/2023 - "The natural naphthoquinol compound deoxyshikonin exhibits anticancer properties, so we hypothesized that it has an apoptotic effect on osteosarcoma U2OS and HOS cells and studied its mechanisms. "
01/01/2023 - "Apoptotic effect and cell arrest of deoxyshikonin in human osteosarcoma cells through the p38 pathway."