HOME
PRODUCTS
COMPANY
CONTACT
FAQ
Research
Dictionary
Pharma
Sign Up
FREE
or
Login
Username:
Password:
Remember login
Login
Send password reminder...
methyl 2- ((3,4- dihydro- 3,4- dioxo- 1- naphthalenyl)amino)benzoate
structure given in first source
Also Known As:
CGS 8515; CGS-8515; Benzoic acid, 2-((3,4-dihydro-3,4-dioxo-1-naphthalenyl)amino)-, methyl ester
Networked:
6
relevant articles (
1
outcomes,
0
trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Organic Chemicals: 133
Hydrocarbons: 1713
Cyclic Hydrocarbons: 97
Aromatic Hydrocarbons: 291
Polycyclic Aromatic Hydrocarbons: 2020
Naphthalenes: 18
Naphthoquinones: 418
methyl 2-((3,4-dihydro-3,4-dioxo-1-naphthalenyl)amino)benzoate: 6
Benzene Derivatives: 17
Benzoates: 426
Aminobenzoates: 1
ortho-Aminobenzoates: 8
methyl 2-((3,4-dihydro-3,4-dioxo-1-naphthalenyl)amino)benzoate: 6
Carboxylic Acids: 973
Carbocyclic Acids
Benzoates: 426
Aminobenzoates: 1
ortho-Aminobenzoates: 8
methyl 2-((3,4-dihydro-3,4-dioxo-1-naphthalenyl)amino)benzoate: 6
Quinones: 434
Naphthoquinones: 418
methyl 2-((3,4-dihydro-3,4-dioxo-1-naphthalenyl)amino)benzoate: 6
Polycyclic Compounds: 6
Polycyclic Aromatic Hydrocarbons: 2020
Naphthalenes: 18
Naphthoquinones: 418
methyl 2-((3,4-dihydro-3,4-dioxo-1-naphthalenyl)amino)benzoate: 6
Related Diseases
1.
Ventricular Fibrillation
06/01/1995 - "
Results showed that although two different platelet-activating factor antagonists have different effects on the incidence of ventricular fibrillation and mortality, they improved the digoxin-induced arrhythmias when they were used either separately or in combination with CGS 8515 or Dazmegrel by implicating that platelet-activating factor has a role on digoxin-induced arrhythmias.
"
2.
Pleurisy (Pleuritis)
01/01/1989 - "
4. CGS 8515, at oral doses as low as 5 mg/kg, significantly suppressed exudate volume and leukocyte migration in the carrageenan-induced pleurisy and sponge models in the rat.
"
04/15/1988 - "
CGS 8515, at oral doses as low as 5 mg/kg, significantly suppressed exudate volume and leukocyte migration in the carrageenan-induced pleurisy and sponge models in the rat.
"
3.
Coronary Occlusion
11/01/1988 - "
BW755c, CGS-8515, and FPL-55712 all prevented an otherwise significant fall in VF threshold during coronary occlusion (p less than 0.01) independent of an effect on effective refractory period, heart rate, or blood pressure.
"
4.
Hypotension (Low Blood Pressure)
04/01/1993 - "
The 1-to 2-h systemic hypotension, caused by TNF-alpha + IL-1 alpha, was not abrogated by either indomethacin or CGS 8515.
"
5.
Anaphylaxis (Anaphylactic Shock)
12/01/1988 - "
5. We conclude that leukotrienes have a major role in guinea-pig cardiac anaphylaxis, and that CGS 8515 has a cardio-protective action.
"
Related Drugs and Biologics
1.
Platelet Activating Factor
2.
Digoxin (Digitek)
3.
dazmegrel
4.
Carrageenan
5.
Interleukin-1alpha (Interleukin 1 alpha)
6.
4,5- Dihydro- 1- (3- (trifluoromethyl)phenyl)- 1H- pyrazol- 3- amine
7.
Leukotrienes
8.
Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
9.
Indomethacin (Indometacin)
10.
FPL 55712