sialosyl-Tn antigen

11/01/1995 - "Several studies have revealed a correlation between sialosyl Tn antigen (STN) and certain clinicopathologic features of various cancers, and that STN is an independent prognostic factor. "
08/01/1994 - "Use of model cell lines to study the biosynthesis and biological role of cancer-associated sialosyl-Tn antigen."
10/27/2015 - "ST6GalNAc1 encodes a sialytransferase that catalyses formation of the cancer-associated sialyl-Tn antigen (sTn), which we find is also induced by androgen exposure. "
01/01/2015 - "Altered protein glycosylation translated by the expression of the sialyl-Tn antigen (STn) and its precursor Tn as well as the activation of the PI3K/Akt/mTOR pathway are cancer-associated events that may hold potential for patient stratification and guided therapy. "
02/01/2013 - "The interaction between Siglec-15 and tumor-associated sialyl-Tn antigen enhances TGF-β secretion from monocytes/macrophages through the DAP12-Syk pathway."

01/01/1996 - "The purpose of this study was to evaluate the prognostic value of Tn and sialyl-Tn antigen expression in human ovarian carcinoma. "
05/08/2007 - "Sialyl-Tn antigen is rarely expressed in normal tissues but is aberrantly expressed in a variety of carcinomas, where it constitutes a marker of poor prognosis. "
10/01/2004 - "The Sialyl-Tn antigen (Neu5Acalpha2-6GalNAc-O-Ser/Thr) is highly expressed in several human carcinomas and is associated with carcinoma aggressiveness and poor prognosis. "
08/01/2000 - "Forty carcinomas (42.6%) were negative and 54 (57.5%) were positive for sialyl Tn antigen. "
01/01/1999 - "High serum concentrations of sialyl Tn antigen in carcinomas of the biliary tract and pancreas."

02/01/2002 - "Prognostic value of expression of sialosyl-Tn antigen in colorectal carcinoma and transitional mucosa."
09/01/2000 - "Prognostic value of circulating sialyl Tn antigen in colorectal cancer patients."
09/01/2000 - "The relationship between circulating sialyl Tn antigen and polypoid or nonpolypoid growth characteristics in colorectal cancer."
08/01/2000 - "A total of 94 advanced colorectal carcinomas were examined for sialyl Tn antigen expression, which was immunohistochemically detected by the monoclonal antibody TKH2. "
08/01/2000 - "Different expression of sialyl Tn antigen between polypoid and nonpolypoid growth types of advanced colorectal carcinoma."

06/21/1996 - "Sialosyl-Tn antigen as a marker of gastric cancer progression: an international study."
10/01/2004 - "We report a case of a 58-year-old man with advanced gastric cancer producing sialyl-Tn antigen (STN). "
12/01/2001 - "To clarify the prognostic value of preoperative serum levels of sialyl Tn antigen (STN) for survival of gastric cancer patients. "
01/01/1998 - "Sialyl-Tn antigen as a useful predictor of poor prognosis in patients with advanced stomach cancer."
07/01/1996 - "Sialosyl Tn antigen expression is associated with the prognosis of patients with advanced gastric cancer."

03/01/1992 - "There is a significant correlation between the positive rates of serum sialyl-Tn antigen and liver metastases, peritoneal dissemination, or lymph node metastases. "
12/01/2001 - "Pre-operative serum levels of sialyl Tn antigen predict liver metastasis and poor prognosis in patients with gastric cancer."
03/15/1995 - "The rate of expression of sialyl Tn antigen in early carcinoma was low, but it increased significantly as depth of invasion increased (P < .05) and was significantly higher in patients with hepatic or lymph node metastasis than in those without such metastasis (P < .01). "
08/01/2001 - "To further study the exceptional lymph node metastases we studied the expression of intestinal trefoil factor and sialyl Tn antigen immunohistochemically on the resected specimen. "
01/01/2016 - "ST6GalNAc I is a sialyltransferase controlling the expression of sialyl-Tn antigen (STn), which is overexpressed in several epithelial cancers, including gastric cancer, and is highly correlated with cancer metastasis. "