clonidine-displacing substance (ClDS)

06/21/2022 - "The management of chronic liver diseases (CLDs) remains a challenge, and identifying effective treatments is a major unmet medical need. "
11/20/2023 - "In this study, we developed and validated a liver stiffness-based machine learning algorithm (ML) for prediction and risk stratification of HCC in various chronic liver diseases (CLDs). "
01/01/2022 - "Mouse models are frequently used to study chronic liver diseases (CLDs). "
12/20/2021 - "The present study aims to assess the sleep characteristics and health-related quality of life (HRQOL) among patients with chronic liver diseases (CLDs), as well as the relationship between them. "
01/01/2021 - "In addition, we discuss translational studies in which metabolic intervention has been used to treat chronic liver diseases (CLDs)."

11/01/2023 - "A common feature among CLDs is an aggressive T cell response resulting in destruction of liver tissue and fibrosis. "
03/26/2022 - "This research increases awareness regarding the connection between sleep features and MHE in patients with cirrhosis and other CLDs. "
03/26/2022 - "Patients with cirrhosis recorded significantly lower PHES scores compared to patients with other CLDs but without cirrhosis (−3.19 ± 3.89 vs. 0.19 ± 2.92, p < 0.05). "
10/01/2021 - "Healthcare expenditures for CLDs or cirrhosis are substantial in the United States, driven disproportionately by acute care in-hospital spending."
10/01/2021 - "From 1996 to 2016, there was a 4.3%/year (95% CI, 2.8%-5.8%) increase in overall healthcare spending for patients with CLDs or cirrhosis, driven by a 17.8%/year (95% CI, 14.5%-21.6%) increase in price and intensity of hospital-based services. "

01/01/2023 - "nLDs were frequently found in hepatocytes of patients with nonalcoholic steatohepatitis, whereas cLDs in NR were absent from the livers of such patients. "
11/01/2022 - "During 27 years of follow-up, among 4 patients with CLDs and the controls, all-cause cumulative mortality was highest among patients with HCV (35.2%), followed by ALD (34.7%) and NAFLD (29.6%). "
10/01/2022 - "Among CLDs, the evidence is relatively consistent and clear for ALD, while clear evidence is limited in other CLDs including HBV, HCV, and NAFLD. "
10/01/2021 - "From 2009 to 2019, regions in Asia and MENA experienced a rise in DALYs attributable to LC-NAFLD (compared to LC from other CLDs), ranging from South Asia (APC = +2.12% vs. -0.94%) to high-income Asia Pacific (APC = -0.07%, p = 0.646 vs. -0.97%). "
10/01/2021 - "There were 168,969 deaths related to LC-NAFLD, accounting for 8.6% of LC deaths from all CLDs. "

01/01/2020 - "This study investigated the effects of anti-microRNA-21 (miR-21) AMO modified with CLDs on breast cancer cells without using reporter assay. "
01/01/2020 - "Therefore, an AMO flanked by CLDs can be a promising strategy for breast cancer treatment."
01/01/2021 - "Our results provide a hypothesis-generating list of potential players in breast cancer progression and offers a new perspective on the role of CLDs in cancer."
11/01/2021 - "Prior studies conducted primarily in white populations have suggested that pre-diagnostic cholesterol lowering drugs (CLDs) improved survival among women with breast cancer (BC). "
01/01/2021 - "Therefore, the purpose of this study was to identify the proteome and assess the characteristics of CLDs in the MCF10CA1a human metastatic breast cancer cell line. "

09/01/2020 - "CC can be helpful for predicting sarcopenia in CLDs."
09/01/2021 - "We sought to assess the prevalence of sarcopenia and its prognostic significance in patients with CLDs at multiple centers in Japan. "
09/01/2020 - "To elucidate the influence of calf circumference (CC) on sarcopenia in patients with chronic liver damages (CLDs, n=525, 255 men). "
05/08/2019 - "In conclusion, sarcopenia can be an independent predictor for depression in CLDs."
03/11/2019 - "In conclusion, Zn deficiency can be an independent predictor for sarcopenia in patients with CLDs."