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Y glycolipid

Fuc alpha1--2-Gal beta1--4GlcNAc(3--1alpha Fuc)beta1--3LaCer; found in gastric carcinoma cells

Also Known As:

Y oligosaccharide

Networked: 8 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Carbohydrates: 22023
- Glycoconjugates: 1353
  - Glycolipids: 2799
    - Glycosphingolipids: 1659
      - Y glycolipid: 8
Lipids: 114793
- Glycolipids: 2799
  - Glycosphingolipids: 1659
    - Y glycolipid: 8
- Membrane Lipids: 1591
  - Sphingolipids: 3208
    - Glycosphingolipids: 1659
      - Y glycolipid: 8

Experts

1.	Edwards, Michael R: 1 article (01/2018)
2.	Howard, Jonathan: 1 article (01/2018)
3.	Liu, Shifang: 1 article (01/2018)
4.	Mehta, Devangi: 1 article (01/2018)
5.	Meka, Ven: 1 article (01/2018)
6.	Prada, Claudia: 1 article (01/2018)
7.	Pultz, Joe: 1 article (01/2018)
8.	Ray, Soma: 1 article (01/2018)
9.	Sheikh, Sarah I: 1 article (01/2018)
10.	von Hehn, Christian: 1 article (01/2018)

Related Diseases

1.	Neoplasms (Cancer) 12/10/1997 - "In addition, purified Le(y) glycolipid from canine intestine augmented the procoagulant activity of CCA-1p, and this augmentation also could be inhibited by FS01 MAb. We conclude that Le(y) glycolipid is a co-factor for the procoagulant activity derived from cancer cells." 12/10/1997 - "Le(y) glycolipid acts as a co-factor for tumor procoagulant activity." 03/01/1991 - "Tumor cell lysis and tumor growth inhibition by the isotype variants of MAb BR55-2 directed against Y oligosaccharide." 01/01/2007 - "Lewis Y oligosaccharide has a terminal alpha1,3-linked fucose residue and elevation of Lewis Y level is seen in many epithelial cancers. " 05/01/1996 - "The murine monoclonal antibody BR55-2 is directed against the tumor-associated antigen Lewis Y oligosaccharide. "
2.	Colorectal Neoplasms (Colorectal Cancer) 06/06/2006 - "Here we describe the production of mAb BR55-2 (IgG2a) in transgenic plants that recognizes the nonprotein tumor-associated antigen Lewis Y oligosaccharide overexpressed in human carcinomas, particularly breast and colorectal cancers. "
3.	Tetanus 01/01/2018 - "In this open-label, multicenter study, patients received 3 vaccinations: (1) tetanus-diphtheria toxoid (Td) to test T-cell-dependent recall response, (2) pneumococcal vaccine polyvalent to test T-cell-independent humoral response, and (3) meningococcal (groups A, C, W-135, and Y) oligosaccharide CRM197 conjugate to test T-cell-dependent neoantigen response. "
4.	Carcinoma (Carcinomatosis) 06/06/2006 - "Here we describe the production of mAb BR55-2 (IgG2a) in transgenic plants that recognizes the nonprotein tumor-associated antigen Lewis Y oligosaccharide overexpressed in human carcinomas, particularly breast and colorectal cancers. "
5.	Adenocarcinoma 03/01/1991 - "IgG3 murine MAb BR55-2 is directed against adenocarcinoma associated Y oligosaccharide. "

Related Drugs and Biologics

1.	Antigens
2.	Monoclonal Antibodies
3.	Immunoglobulin G (IgG)
4.	Pneumococcal Vaccines (Pneumococcal Polysaccharide Vaccine)
5.	Peptides (Polypeptides)
6.	Fucose
7.	Diphtheria Toxoid (Vaccine, Diphtheria)
8.	Complement System Proteins (Complement)
9.	Carbohydrates
10.	CRM197 (non-toxic variant of diphtheria toxin)