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clidinium (clidinium bromide)

see also record for clidinium compounds; RN given refers to cpd without isomeric designation

Also Known As:

clidinium bromide; N-methyl quinuclidinyl benzilate; clidinium iodide; clidinium iodide, (+-)-isomer; clidinium iodide, 11C-labeled; clidinium iodide, 3H-labeled; clidinium, 1-(methyl-11C)-labeled; clidinium, 11C-labeled; clidinium, 3H-labeled

Networked: 9 relevant articles (1 outcomes, 2 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1.	Pirsalami, Fatema: 1 article (03/2015)
2.	Moezi, Leila: 1 article (03/2015)
3.	Inaloo, Soroor: 1 article (03/2015)
4.	Chorami, Maryam: 1 article (01/2013)
5.	Naderi, Nosratollah: 1 article (01/2013)
6.	Mirsattari, Dariush: 1 article (01/2013)
7.	Zojaji, Homayoun: 1 article (01/2013)
8.	Shalmani, Hamid Mohaghegh: 1 article (01/2013)
9.	Moghimi-Dehkordi, Bijan: 1 article (01/2013)
10.	Edwards, K: 1 article (06/2009)

Related Diseases

1.	Irritable Bowel Syndrome (Syndrome, Irritable Bowel) 04/20/1978 - "To determine the effect of a standard meal on colonic myoelectrical and motor activity in the irritable-bowel syndrome and to determine the effect of a single dose of an oral anticholinergic drug (clidinium bromide) on this response, we studied 10 patients. " 12/01/1989 - "Among 169 patients with irritable bowel syndrome (IBS), standard therapy (with clidinium bromide, chlordiazepoxide and isaphaghulla), a compound Ayurvedic preparation (with Aegle marmelos correa plus Bacopa monniere Linn) along with a matching placebo were given in a double blind randomised trial for 6 wk. The Ayurvedic preparation in 57 patients was found effective in 64.9 per cent, while standard therapy (60 patients) was useful in 78.3 per cent. " 06/01/2009 - "Clidinium bromide (N-methyl-quinuclidinyl-benzylate) is a rarely used antimuscarinic drug that is marketed in combination with chlordiazepoxide as an antispasmodic for use in irritable bowel syndrome. "
2.	Dyspepsia (Indigestion) 01/01/2013 - "This study aimed to evaluate the success of H.pylori eradication therapy in patients with dyspepsia by therapeutics regimes with and without clidinium C. "
3.	Seizures (Seizure) 03/01/2015 - "In conclusion, loperamide- or clidinium-induced constipated mice are more prone to seizure which might confirm the belief of patients and physicians about constipation as a trigger of seizure. " 03/01/2015 - "Moreover loperamide- or clidinium-induced constipation decreased latencies to, clonic, and tonic seizures and death in the intraperitoneal pentylenetetrazole model of mice. " 03/01/2015 - "The current investigation evaluated the effects of constipation induced by loperamide (a peripheral μ-opioid receptor agonist without effect on central nervous system receptors) and clidinium (a quaternary amine antimuscarinic agent with reduced central nervous system effects) on two different seizure models of mice: (1) myoclonic, clonic, and generalized tonic seizures and death induced by intraperitoneal administration of pentylenetetrazole and (2) clonic seizure threshold induced by intravenous infusion of pentylenetetrazole. "
4.	Thrombocytopenic Purpura (Thrombopenic Purpura) 07/23/2001 - "Acute thrombocytopenic purpura in a patient treated with chlordiazepoxide and clidinium."
5.	Peptic Ulcer (Peptic Ulcers) 05/01/1962 - "[Treatment of gastroduodenal peptic ulcer with the combination of clidinium bromide and chlordiazepoxide. "

Related Drugs and Biologics

1.	Chlordiazepoxide (Elenium)
2.	Opioid Receptors (Opioid Receptor)
3.	Pentylenetetrazole (Metrazol)
4.	Loperamide (Imodium)
5.	clidinium drug combination chlordiazepoxide (Librax)

Related Therapies and Procedures

1.	Therapeutics
2.	Intravenous Infusions