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GDP-4-keto-6-deoxymannose

Also Known As:

guanosine diphosphate-4-keto-6-deoxy-D-mannose

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Purines: 651
      - Purine Nucleotides: 140
        Guanine Nucleotides: 675
        Guanosine Diphosphate: 1407
        Guanosine Diphosphate Sugars
        Guanosine Diphosphate Mannose: 22
        GDP-4-keto-6-deoxymannose: 2
Carbohydrates: 22023
- Glycosides: 2119
  - Nucleotides: 15763
    - Nucleoside Diphosphate Sugars
      - Guanosine Diphosphate Sugars
        Guanosine Diphosphate Mannose: 22
        GDP-4-keto-6-deoxymannose: 2
Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleotides: 15763
  - Ribonucleotides: 307
    - Guanine Nucleotides: 675
      - Guanosine Diphosphate: 1407
        Guanosine Diphosphate Sugars
        Guanosine Diphosphate Mannose: 22
        GDP-4-keto-6-deoxymannose: 2
    - Nucleoside Diphosphate Sugars
      - Guanosine Diphosphate Sugars
        Guanosine Diphosphate Mannose: 22
        GDP-4-keto-6-deoxymannose: 2
  - Purine Nucleotides: 140
    - Guanine Nucleotides: 675
      - Guanosine Diphosphate: 1407
        Guanosine Diphosphate Sugars
        Guanosine Diphosphate Mannose: 22
        GDP-4-keto-6-deoxymannose: 2

Experts

1.	Cook, Paul D: 1 article (06/2009)
2.	Holden, Hazel M: 1 article (06/2009)
3.	Kubiak, Rachel L: 1 article (06/2009)
4.	Toomey, Daniel P: 1 article (06/2009)
5.	Albermann, C: 1 article (09/2000)
6.	Distler, J: 1 article (09/2000)
7.	Piepersberg, W: 1 article (09/2000)

Related Diseases

1.

Dehydration (Water Stress)

06/16/2009 - "The biosynthetic pathways for these two sugars begin with the formation of GDP-mannose from d-mannose 1-phosphate and GTP followed by the subsequent dehydration and oxidation of GDP-mannose to yield GDP-4-keto-6-deoxymannose. "
09/01/2000 - "The biosynthetic pathway of GDP-L-fucose starts with a dehydration of GDP-D-mannose catalyzed by GDP-D-mannose 4,6-dehydratase (Gmd) creating GDP-4-keto-6-deoxymannose which is subsequently converted by the GDP-4-keto-6-deoxy-D-mannose 3,5-epimerase-4-reductase (WcaG; GDP-beta-L-fucose synthetase) to GDP-beta-L-fucose. "

Related Drugs and Biologics

1.	Mannose (D-Mannose)
2.	Ligases (Synthetase)
3.	Guanosine Triphosphate (GTP)
4.	Guanosine Diphosphate Mannose (GDP Mannose)
5.	Guanosine Diphosphate (GDP)
6.	Fucose
7.	Sugars