polyerga neu

02/01/2000 - "Patients with inoperable head and neck cancer were treated with a spleen peptide preparation (Polyerga) in a phase III randomized, placebo-controlled double-blind study during chemotherapy (cisplatin/carboplatin, 5-fluorouracil) to investigate further the efficacy of this peptide preparation as supportive treatment under chemotherapy. "

01/01/1996 - "These in vitro studies were extended to in vivo application using C57B1/GoZgr mice injected i.v. with melanoma cells pretreated with Polyerga in vitro or previously not treated. "
01/01/1996 - "A significant difference to the control values was noticed in each group that used Polyerga, regardless of the exposure of melanoma cells to Polyerga in vitro, in vivo or to combined treatment. "
01/01/1996 - "Polyerga preparation is thus active against melanoma cells, particularly in vivo and if combined with chemotherapy."
01/01/1996 - "However, 24-h incubation of melanoma cells in the presence of 150 micrograms of Polyerga per ml significantly reduced the number of tumor cell colonies in comparison to the corresponding cell cultures previously not exposed to Polyerga. "
01/01/1996 - "Further, the incidence of experimental lung metastases of melanoma cells in mice was significantly reduced if we used Polyerga preparations. "

01/01/1996 - "The aim of our investigation was to determine whether Polyerga is active directly against tumor cells or whether its activity is manifested by modulating immune and other possible abilities of the organism. "
01/01/1996 - "However, 24-h incubation of melanoma cells in the presence of 150 micrograms of Polyerga per ml significantly reduced the number of tumor cell colonies in comparison to the corresponding cell cultures previously not exposed to Polyerga. "
02/01/1998 - "Among the preparations that have beneficial effects for the cancer bearing organism are preparations of spleen peptides (Polyerga). "

01/01/1996 - "Further, the incidence of experimental lung metastases of melanoma cells in mice was significantly reduced if we used Polyerga preparations. "
01/01/1996 - "The smallest incidence of experimental lung metastases was observed in the group exposed to the combination of DTIC and Polyerga. "
01/01/1996 - "Porcine splenic peptides (Polyerga) decrease the number of experimental lung metastases in mice."
02/01/1998 - "Spleen peptides (Polyerga) inhibit development of artificial lung metastases of murine mammary carcinoma and increase efficiency of chemotherapy in mice."

07/01/1996 - "We evaluated the effect of low molecular weight glycoproteins isolated from animal spleen (Polyerga) in ten patients with biopsy proven chronic HBV infection with ongoing replication. "